FB2025_01 , released February 20, 2025
Allele: Dmel\TrpA1UAS.A.cGa
Open Close
General Information
Symbol
Dmel\TrpA1UAS.A.cGa
Species
D. melanogaster
Name
FlyBase ID
FBal0359450
Feature type
allele
Associated gene
Dmel\TrpA1
Associated Insertion(s)
Carried in Construct
P{UAS-TrpA1-A.G}
Also Known As
UAS-TrpA1-A
Key Links
Transgenic product class
wild_type
(Gu et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Gu et al., 2019)
Mutagen
in vitro construct
(Gu et al., 2019)
Progenitor genotype
Carried in construct
P{UAS-TrpA1-A.G}
Cytology
Description

UASt regulatory sequences drive expression of the TrpA1 'A' isoform (TrpA1 isoform nomenclature of FBrf0211878 and FBrf0217493, corresponds to TrpA1-PI of the FlyBase FB2018_05 release).

(Gu et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
TrpA1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of TrpA1UAS.A.cGa under the control of Scer\GAL4ppk.PG leads to rolling behavior in response to lower temperatures compared to control third instar larvae.

      Expression of TrpA1UAS.A.cGa under the control of Scer\GAL4elav.PLu leads to seizure-like immobilization in response to heating to 29[o]C compared to control adults.

      (Gu et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TrpA1UAS.A.cGa
      Name Synonyms
      Secondary FlyBase IDs
        References (3)