FB2025_01 , released February 20, 2025
Allele: Scer\GAL4RluA-1.MI06897-TG4.0
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General Information
Symbol
Scer\GAL4RluA-1.MI06897-TG4.0
Species
S. cerevisiae
Name
FlyBase ID
FBal0365312
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Mi{Trojan-GAL4.0}RluA-1MI06897-TG4.0
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Song et al., 2020)
Progenitor genotype
Mi{MIC}RluA-1MI06897
(Song et al., 2020)
Associated Insertion(s)
Mi{Trojan-GAL4.0}RluA-1MI06897-TG4.0
Cytology
Description

The attP cassette in the Mi{MIC}RluA-1MI06897 insertion has been replaced with a Trojan GAL4 cassette that contains a splice acceptor site followed by the T2A peptide, the GAL4 coding sequence and an Hsp70 transcription termination signal. Thus GAL4 expression is driven by the native RluA-1 regulatory sequences.

(Song et al., 2020)
Allele components
Component
Use(s)
Inserted element
Mi{Trojan-GAL4.0}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      external sensory organ
      (Song et al., 2020)
      larval abdominal dorsal multidendritic neuron dda1
      (Song et al., 2020)
      abdominal dorsal bipolar neuron dbp
      (Song et al., 2020)
      larval dorsal multidendritic neuron ddaD
      (Song et al., 2020)
      larval dorsal multidendritic neuron ddaE
      (Song et al., 2020)
      larval dorsal multidendritic neuron ddaB
      (Song et al., 2020)
      larval dorsal multidendritic neuron ddaA
      (Song et al., 2020)
      larval dorsal multidendritic neuron ddaF
      (Song et al., 2020)
      larval dorsal multidendritic neuron ddaC
      (Song et al., 2020)
      sensory neuron

      Comment: axonal projections

      (Song et al., 2020)
      ventral nerve cord
      (Song et al., 2020)
      larval central nervous system | restricted
      (Song et al., 2020)
      adult stage
      adult central brain | restricted
      (Song et al., 2020)
      adult optic lobe
      (Song et al., 2020)
      Additional Information
      Statement
      Reference

      Reporter expression is observed in the peripheral sensory neurons in each segment of the larval body wall. In the dorsal cluster, signal was detected in the cell body and dendrites of all four classes of multidendritic neurons, dorsal multiple dendrite neuron dmd1, external sensory and dorsal bipolar dendritic neurons. In the ventral nerve cord, signal is seen in axonal projections of the sensory neurons. In the adult brain, significant signal was observed in the optic lobes and in small clusters in the central brain.

      (Song et al., 2020)
       
      Marker for
      Reflects expression of
      RluA-1
      (Song et al., 2020)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4RluA-1.MI06897-TG4.0
      Name Synonyms
      Secondary FlyBase IDs
        References (1)