FlyBase Allele Report: Dmel\Fas3[UAS.cLa]

General Information

Symbol

Dmel\Fas3^UAS.cLa

Species

D. melanogaster

Name

UAS construct a of Li

FlyBase ID

FBal0365412

Feature type

allele

Associated gene

Dmel\Fas3

Associated Insertion(s)

Carried in Construct

P{UAS-Fas3.L}

Key Links

Transgenic product class

wild_type

(Li et al., 2020)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Li et al., 2020)

Mutagen

in vitro construct

(Li et al., 2020)

Progenitor genotype

Carried in construct

P{UAS-Fas3.L}

Cytology

Description

10xUAS regulatory sequences and a synthetic core promoter drive expression of the Fas3 coding sequence.

(Li et al., 2020)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Fas3

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates childhood spinal muscular atrophy

modeled by Smn^Δ

(Li et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor of decreased body size | larval stage phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of decreased size | larval stage phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of abnormal locomotor behavior | larval stage phenotype of snRNA:U12^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor of abnormal locomotor behavior | larval stage phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of snRNA:U12^Δ

(Li et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of muscle cell of A1-7 ventral longitudinal muscle 3 | larval stage phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of embryonic/larval neuromuscular junction | larval stage phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of NMJ bouton | larval stage | decreased number phenotype of Smn^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of NMJ bouton | larval stage | decreased number phenotype of snRNA:U12^Δ

(Li et al., 2020)

Scer\GAL4^elav-C155/Fas3^UAS.cLa is a suppressor | partially of embryonic/larval neuromuscular junction | larval stage phenotype of snRNA:U12^Δ

(Li et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Fas3^UAS.cLa

Name Synonyms

UAS construct a of Li

Secondary FlyBase IDs

References (1)

Report Sections

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