FB2025_01 , released February 20, 2025
Allele: Dmel\PRAS40RNAi.WIZ.UAS
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General Information
Symbol
Dmel\PRAS40RNAi.WIZ.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0368840
Feature type
allele
Associated gene
Dmel\PRAS40
Associated Insertion(s)
Carried in Construct
P{UAS-PRAS40.RNAi.WIZ}
Key Links
Transgenic product class
RNAi_reagent
(Son and Choi, 2020)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Son and Choi, 2020)
Mutagen
in vitro construct
(Son and Choi, 2020)
Progenitor genotype
Carried in construct
P{UAS-PRAS40.RNAi.WIZ}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat of a 501bp PRAS40 sequence (targets unique sequences in the PRAS40 3' coding region).

(Son and Choi, 2020)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
PRAS40
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      PRAS40RNAi.WIZ.UAS/Scer\GAL4ey.PU is a non-enhancer of visible | dominant phenotype of L2

      (Son and Choi, 2020)
      NOT Suppressor of
      Statement
      Reference

      PRAS40RNAi.WIZ.UAS/Scer\GAL4ey.PU is a non-suppressor of visible | dominant phenotype of L2

      (Son and Choi, 2020)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      PRAS40RNAi.WIZ.UAS/Scer\GAL4ey.PU is a non-enhancer of eye phenotype of L2

      (Son and Choi, 2020)
      NOT Suppressor of
      Statement
      Reference

      PRAS40RNAi.WIZ.UAS/Scer\GAL4ey.PU is a non-suppressor of eye phenotype of L2

      (Son and Choi, 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      PRAS40RNAi.WIZ.UAS/Scer\GAL4ey.PU rescues PRAS40UAS.cCa

      (Son and Choi, 2020)
      Comments

      Co-expression of PRAS40dsRNA.WIZ.UAS fully rescues the small eye phenotype caused by expression of PRAS40UAS.cCa under the control of Scer\GAL4ey.PU.

      (Son and Choi, 2020)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      PRAS40RNAi.WIZ.UAS
      PRAS40dsRNA.WIZ.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)