CTA9991122TGG
L195W | TER94-PA; L220W | TER94-PC; L153W | TER94-PD; L220W | TER94-PE
L195W
Analogous L198W mutation in human VCP implicated in FTDALS6 and/or IBMPFD1 (MSP-1) disease; mutation carried on in vitro construct; site of nucleotide substitution in fly gene inferred by FlyBase curator based on reported amino acid change.
TER94L195W.sfGFP heterozygotes show a progressive decrease in climbing ability in males only. Their larval body wall muscles are disorganized and show smaller nuclei with disorganized lamina, and show lysosomal defects.