FlyBase Allele Report: Dmel\Ras85D[V12.QUAS.cLa]

General Information

Symbol

Dmel\Ras85D^V12.QUAS.cLa

Species

D. melanogaster

Name

FlyBase ID

FBal0370859

Feature type

allele

Associated gene

Dmel\Ras85D

Associated Insertion(s)

Carried in Construct

PBac{QUAS-Ras85D.V12.L}

Also Known As

QUAS-Ras^V12

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Lodge et al., 2021)

Progenitor genotype

Carried in construct

PBac{QUAS-Ras85D.V12.L}

Cytology

Description

QUAS regulatory sequences drive expression of an oncogenic form of Ras85D.

(Lodge et al., 2021)

Allele components

Component

Use(s)

Regulatory region(s)

QUAS

binary expression system - regulatory region

Encoded product / tool

Ras85D

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of cancer

CEA with scrib^{QUAS.HMS01490}

(Bakopoulos et al., 2023, Lodge et al., 2021)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has atrophy | larval stage phenotype, suppressible | partially by Scer\GAL4^Mhc.PK/Akt^UAS.Exel

(Bakopoulos et al., 2023)

NOT suppressed by

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has atrophy | larval stage phenotype, non-suppressible by Scer\GAL4^Mhc.PK/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has atrophy | larval stage phenotype, non-suppressible by Akt^UAS.Exel/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has atrophy | larval stage phenotype, non-suppressible by Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Other

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has atrophy | larval stage phenotype

(Bakopoulos et al., 2023)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has extracellular matrix | larval stage phenotype, enhanceable by Scer\GAL4^Mhc.PK/Akt^UAS.Exel

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has extracellular matrix | larval stage phenotype, enhanceable by SPARC^GD5660/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, enhanceable by SPARC^GD5660/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, enhanceable by SPARC^GD5660/Scer\GAL4^r4

(Bakopoulos et al., 2023)

NOT Enhanced by

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, non-enhanceable by Ras85D^V12.UAS/Scer\GAL4^phtm.PU

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has embryonic/larval fat body | larval stage phenotype, non-enhanceable by Ras85D^V12.UAS/Scer\GAL4^phtm.PU

(Bakopoulos et al., 2023)

Suppressed by

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by InR^A1325D.UAS/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by InR^A1325D.UAS/Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has A1-7 ventral longitudinal muscle 3 | larval stage phenotype, suppressible | partially by Scer\GAL4^Mhc.PK/Akt^UAS.Exel

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has embryonic/larval fat body | larval stage phenotype, suppressible by Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has extracellular matrix | larval stage phenotype, suppressible by Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible by vkg^UAS.GFP/Scer\GAL4^r4/Col4a1^UAS.GFP

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by sog^UAS.Tag:HA/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by sog^UAS.Tag:HA/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by Scer\GAL4^Mef2.PU/sog^UAS.Tag:HA

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by Scer\GAL4^Mef2.PU/sog^UAS.Tag:HA

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible by vkg^UAS.GFP/Scer\GAL4^r4/Col4a1^UAS.GFP

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has extracellular matrix | larval stage phenotype, suppressible by SPARC^UAS.cUa/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by SPARC^UAS.cUa/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by SPARC^UAS.cUa/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has extracellular matrix | larval stage phenotype, suppressible by Scer\GAL4^r4/Rab10^RNAi.UAS.cUa

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by Scer\GAL4^r4/Rab10^RNAi.UAS.cUa

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by Scer\GAL4^r4/Rab10^RNAi.UAS.cUa

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by Akt^UAS.Exel/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by InR^A1325D.UAS/Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by InR^A1325D.UAS/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, suppressible | partially by Scer\GAL4^Mhc.PK/Akt^UAS.Exel

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has larval muscle system | larval stage phenotype, suppressible | partially by Akt^UAS.Exel/Scer\GAL4^r4

(Bakopoulos et al., 2023)

NOT suppressed by

Statement

Reference

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has A1-7 ventral longitudinal muscle 3 | larval stage phenotype, non-suppressible by Scer\GAL4^Mhc.PK/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has A1-7 ventral longitudinal muscle 3 | larval stage phenotype, non-suppressible by Akt^UAS.Exel/Scer\GAL4^r4

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has A1-7 ventral longitudinal muscle 3 | larval stage phenotype, non-suppressible by Scer\GAL4^r4/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, non-suppressible by Scer\GAL4^Mhc.PK/Mad^JF01264

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has muscle attachment site | larval stage phenotype, non-suppressible by Ras85D^V12.UAS/Scer\GAL4^phtm.PU

(Bakopoulos et al., 2023)

Ncra\QF^QF2.Act5C.PL, Ras85D^V12.QUAS.cLa, scrib^{QUAS.HMS01490} has embryonic/larval fat body | larval stage phenotype, non-suppressible by Ras85D^V12.UAS/Scer\GAL4^phtm.PU

(Bakopoulos et al., 2023)

Other

Statement

Reference

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Ras85D^V12.QUAS.cLa

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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