FlyBase Allele Report: Dmel\Rm62[RNAi.UAS.cUa]

General Information

Symbol

Dmel\Rm62^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0374363

Feature type

allele

Associated gene

Dmel\Rm62

Associated Insertion(s)

Carried in Construct

P{UAS-Rm62.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Rm62.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of an RNAi line that targets Rm62.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Rm62

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates amyotrophic lateral sclerosis type 6

modeled by Hsap\FUS^UAS.Tag:HA

(Fortuna et al., 2021)

modeled by Hsap\FUS^{R518K.UAS.Tag:HA}

(Fortuna et al., 2021)

modeled by Hsap\FUS^{R521C.UAS.Tag:HA}

(Fortuna et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is an enhancer of visible | adult stage phenotype of Hsap\FUS^{R518K.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is an enhancer of visible | adult stage phenotype of Hsap\FUS^{R521C.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is an enhancer of visible | adult stage phenotype of Hsap\FUS^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

NOT Enhancer of

Statement

Reference

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-enhancer of visible | adult stage phenotype of Hsap\TARDBP^{M337V.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^30.UAS.EGFP

(Fortuna et al., 2021)

NOT Suppressor of

Statement

Reference

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^30.UAS.EGFP

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage phenotype of Hsap\TARDBP^{M337V.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Phenotype Manifest In

Enhancer of

Statement

Reference

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\FUS^{R518K.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\FUS^{R521C.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\FUS^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

NOT Enhancer of

Statement

Reference

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-enhancer of eye phenotype of Hsap\TARDBP^{M337V.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^30.UAS.EGFP

(Fortuna et al., 2021)

NOT Suppressor of

Statement

Reference

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^30.UAS.EGFP

(Fortuna et al., 2021)

Rm62^RNAi.UAS.cUa, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Hsap\TARDBP^{M337V.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Fortuna et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Rm62^RNAi.UAS.cUa

Rm62^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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