Sequence analysis shows that P{PTT-GA}pAbpPTT-GA is located in the second intron of pAbp at position 1942 when counting from the gene transcription start site.
Homo- or hemizygous pAbp37-2 is zygotic lethal.
In pAbp37-2 mutant germline clones oogenesis does not proceed further than stages 5-6. pAbp37-2 mutant germline clones show a variety of phenotypes in stages 5-6. These include small oocytes, mispositioned oocytes, packaging defects producing egg chambers with supernumerary nurse cells and two oocytes, polytene nurse cells and multilayered follicle cells. Some of these phenotypes may also be due to lack of pAbp in the follicle cells.
Df(3R)p-XT103/+, pAbp37-2 has female sterile phenotype
Df(3R)p-XT103/+, pAbp37-2 has embryo phenotype
Df(3R)p-XT103/+, pAbp37-2 has karyosome phenotype
Df(3R)p-XT103/+, pAbp37-2 has oocyte | oogenesis stage S7 phenotype
+/Df(3R)BSC506, pAbp37-2 has embryo phenotype
Df(3R)p-XT26/+, pAbp37-2 has embryo phenotype
The BicD1/+ mutant embryonic phenotypes are suppressed by pAbp37-2/+.
The suppression of the BicD1/+ embryonic phenotypes by pAbp37-2/+ is partially reverted by one copy of pAbp+t7.8.
Females transheterozygous for pAbp37-2 and the osk deficiency Df(3R)p-XT103 produce karyosome fragmentation defects and oogenesis mostly arrests at stage 7.
Females double heterozygous for pAbp37-2 and either one three deficiencies Df(3R)p-XT103, Df(3R)BSC506 and Df(3R)p-XT26 produce much more frequently embryos with strong posterior phenotypes than females heterozygous for each of these mutations alone.
Females double heterozygous for pAbp37-2 and osk187 produce much more frequently embryos with strong posterior phenotypes than females heterozygous for each of these mutations alone.
Females double heterozygous for pAbp37-2 and oskA87 produce much more frequently embryos with strong posterior phenotypes than females heterozygous for each of these mutations alone.
