FlyBase Allele Report: Hsap\U2AF2[UAS.cLa]

General Information

Symbol

Hsap\U2AF2^UAS.cLa

Species

H. sapiens

Name

UAS construct a of Li

FlyBase ID

FBal0398126

Feature type

allele

Associated gene

Hsap\U2AF2

Associated Insertion(s)

Carried in Construct

P{UAS-hU2AF2.L}

Key Links

Transgenic product class

wild_type

(Li et al., 2024)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Li et al., 2024)

Mutagen

in vitro construct

(Li et al., 2024)

Progenitor genotype

Carried in construct

P{UAS-hU2AF2.L}

Cytology

Description

UAS sequences regulate expression of wild-type Hsap\U2AF2.

(Li et al., 2024)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsap\U2AF2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU is a suppressor of lethal - all die before end of P-stage phenotype of Scer\GAL4^elav.PU, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU is a suppressor of decreased size | larval stage phenotype of Scer\GAL4^elav.PU, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^elav.PU, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^Toll-6-D42 is a suppressor of abnormal heat stress response | adult stage phenotype of Scer\GAL4^Toll-6-D42, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^Toll-6-D42 is a suppressor of paralytic | adult stage phenotype of Scer\GAL4^Toll-6-D42, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^ppk.PG is a suppressor of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4^ppk.PG, U2af50^JF02693

(Li et al., 2024)

Other

Statement

Reference

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU, U2af50^JF02693 has partially lethal - majority live phenotype

(Li et al., 2024)

Phenotype Manifest In

Suppressor of

Statement

Reference

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU is a suppressor | partially of vertical lobe of larval mushroom body | larval stage phenotype of Scer\GAL4^elav.PU, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU is a suppressor of larval brain | larval stage phenotype of Scer\GAL4^elav.PU, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^elav.PU is a suppressor of medial lobe of larval mushroom body | larval stage phenotype of Scer\GAL4^elav.PU, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^ppk.PG is a suppressor of dendrite | larval stage phenotype of Scer\GAL4^ppk.PG, U2af50^JF02693

(Li et al., 2024)

Hsap\U2AF2^UAS.cLa, Scer\GAL4^ppk.PG is a suppressor of embryonic/larval sensory neuron | larval stage phenotype of Scer\GAL4^ppk.PG, U2af50^JF02693

(Li et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\U2AF2^UAS.cLa

Name Synonyms

UAS construct a of Li

Secondary FlyBase IDs

References (1)

Report Sections

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