FlyBase Allele Report: Dmel\TER94[AA.UAS.cLa.Tag:V5]

General Information

Symbol

Dmel\TER94^{AA.UAS.cLa.Tag:V5}

Species

D. melanogaster

Name

FlyBase ID

FBal0402351

Feature type

allele

Associated gene

Dmel\TER94

Associated Insertion(s)

Carried in Construct

P{UAS-TER94.AA.V5.L}

Key Links

Transgenic product class

missense_variant

(Li et al., 2024)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Li et al., 2024)

Mutagen

in vitro construct

(Li et al., 2024)

Progenitor genotype

Carried in construct

P{UAS-TER94.AA.V5.L}

Cytology

Description

UAS sequences regulate expression of a mutated form of TER94 in which the ATP-binding sites have been mutated (amino acid replacements K248A and K521A). The coding sequence is tagged with Tag:V5.

(Li et al., 2024)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

TER94

Tagged with

Tag:V5

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^nub.PU

(Li et al., 2024)

decreased size | adult stage, with Scer\GAL4^ptc.PU

(Li et al., 2024)

decreased size | adult stage, with Scer\GAL4^sd.PU

(Li et al., 2024)

increased cell death | larval stage, with Scer\GAL4^sd.PU

(Li et al., 2024)

visible | adult stage, with Scer\GAL4^nub.PU

(Li et al., 2024)

visible | adult stage, with Scer\GAL4^sd.PU

(Li et al., 2024)

Phenotype Manifest In

wing, with Scer\GAL4^nub.PU

(Li et al., 2024)

wing, with Scer\GAL4^ptc.PU

(Li et al., 2024)

wing, with Scer\GAL4^sd.PU

(Li et al., 2024)

wing disc | larval stage, with Scer\GAL4^sd.PU

(Li et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has decreased size | adult stage phenotype, suppressible | partially by kibra^JF03098/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has decreased size | adult stage phenotype, suppressible | partially by Mer^JF02841, Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has decreased size | adult stage phenotype, suppressible by yki^UAS.cUa/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has decreased size | adult stage phenotype, suppressible by hpo^HMS00006/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has decreased size | adult stage phenotype, suppressible by mats^HMS00475/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has decreased size | adult stage phenotype, suppressible | partially by ex^{TH201501137.S}/Scer\GAL4^ptc.PU

(Li et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has wing phenotype, suppressible by yki^UAS.cUa/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has wing phenotype, suppressible by hpo^HMS00006/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has wing phenotype, suppressible by mats^HMS00475/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has wing phenotype, suppressible | partially by ex^{TH201501137.S}/Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has wing phenotype, suppressible | partially by Mer^JF02841, Scer\GAL4^ptc.PU

(Li et al., 2024)

Scer\GAL4^ptc.PU, TER94^{AA.UAS.cLa.Tag:V5} has wing phenotype, suppressible | partially by kibra^JF03098/Scer\GAL4^ptc.PU

(Li et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

TER94^{AA.UAS.cLa.Tag:V5} is partially rescued by Scer\GAL4^nub.PU/TER94^{UAS.cLa.Tag:V5}

(Li et al., 2024)

TER94^{AA.UAS.cLa.Tag:V5} is partially rescued by Scer\GAL4^sd.PU/TER94^{UAS.cLa.Tag:V5}

(Li et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

TER94^{AA.UAS.cLa.Tag:V5}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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