FB2025_01 , released February 20, 2025
Allele: Dmel\inscK305R
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General Information
Symbol
Dmel\inscK305R
Species
D. melanogaster
Name
FlyBase ID
FBal0403400
Feature type
allele
Associated gene
Dmel\insc
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Yeh et al., 2024)
gene targeting by homologous recombination
(Yeh et al., 2024)
Progenitor genotype
Cytology
Description

Amino acid replacement: K305R.

(Yeh et al., 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
2R:20,824,303..20,824,304 [-]
Nucleotide change:

AA20824304CG

Reported nucleotide change:

AA?CG

Amino acid change:

K305R | insc-PA

Reported amino acid change:

K305R

(Yeh et al., 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      inscK305R is rescued by inscUAS.cKa/Scer\GAL4elav.PLu

      (Yeh et al., 2024)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dInscK305R
      (Yeh et al., 2024)
      inscK305R
      Name Synonyms
      Secondary FlyBase IDs
        References (1)