FlyBase Allele Report: Hsap\RBBP5[UAS.Tag:HA]

General Information

Symbol

Hsap\RBBP5^UAS.Tag:HA

Species

H. sapiens

Name

FlyBase ID

FBal0406613

Feature type

allele

Associated gene

Hsap\RBBP5

Associated Insertion(s)

Carried in Construct

PBac{UAS-hRBBP5.HA}

Key Links

Transgenic product class

cDNA

(Huang et al., 2024)

wild_type

(Huang et al., 2024)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Huang et al., 2024)

wild_type

(Huang et al., 2024)

Mutagen

in vitro construct

(Huang et al., 2024)

Progenitor genotype

Carried in construct

PBac{UAS-hRBBP5.HA}

Cytology

Description

UAS regulatory sequences drive expression of Hsap\RBBP5 cDNA (NM_005057.4) tagged with Tag:HA.

(Huang et al., 2024)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsap\RBBP5

Tagged with

Tag:HA

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body size | larval stage, with Scer\GAL4^Act5C.PI

(Huang et al., 2024)

decreased cell number | larval stage, with Scer\GAL4^da.PU

(Huang et al., 2024)

decreased size | adult stage, with Scer\GAL4^ey.3.5.Exel

(Huang et al., 2024)

decreased size | larval stage, with Scer\GAL4^Act5C.PI

(Huang et al., 2024)

decreased size | larval stage, with Scer\GAL4^da.PU

(Huang et al., 2024)

lethal, with Scer\GAL4^Act5C.PI

(Huang et al., 2024)

viable, with Scer\GAL4^elav.PLu

(Huang et al., 2024)

viable, with Scer\GAL4^ey.3.5.Exel

(Huang et al., 2024)

viable, with Scer\GAL4^repo

(Huang et al., 2024)

visible | adult stage, with Scer\GAL4^ey.3.5.Exel

(Huang et al., 2024)

Phenotype Manifest In

embryonic/larval posterior spiracle | larval stage, with Scer\GAL4^Act5C.PI

(Huang et al., 2024)

eye, with Scer\GAL4^ey.3.5.Exel

(Huang et al., 2024)

intermediate neuronal progenitor | decreased number | larval stage, with Scer\GAL4^da.PU

(Huang et al., 2024)

larval brain, with Scer\GAL4^Act5C.PI

(Huang et al., 2024)

larval brain, with Scer\GAL4^da.PU

(Huang et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Hsap\RBBP5^UAS.Tag:HA/Scer\GAL4^{Rbbp5-CR70469-KO-kG4} is an enhancer of decreased size | larval stage phenotype of Rbbp5^{CR70469-KO-kG4}/Df(3L)BSC447

(Huang et al., 2024)

Hsap\RBBP5^UAS.Tag:HA/Scer\GAL4^{Rbbp5-CR70469-KO-kG4} is an enhancer of decreased cell number | larval stage phenotype of Rbbp5^{CR70469-KO-kG4}/Df(3L)BSC447

(Huang et al., 2024)

Phenotype Manifest In

Enhancer of

Statement

Reference

Hsap\RBBP5^UAS.Tag:HA/Scer\GAL4^{Rbbp5-CR70469-KO-kG4} is an enhancer of larval brain phenotype of Rbbp5^{CR70469-KO-kG4}/Df(3L)BSC447

(Huang et al., 2024)

Hsap\RBBP5^UAS.Tag:HA/Scer\GAL4^{Rbbp5-CR70469-KO-kG4} is an enhancer of intermediate neuronal progenitor | larval stage | decreased number phenotype of Rbbp5^{CR70469-KO-kG4}/Df(3L)BSC447

(Huang et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hsap\RBBP5^UAS.Tag:HA

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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