FB2025_05 , released December 11, 2025
Allele: Dmel\POLDIP2KO1
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General Information
Symbol
Dmel\POLDIP2KO1
Species
D. melanogaster
Name
FlyBase ID
FBal0407845
Feature type
allele
Associated gene
Dmel\POLDIP2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Wang et al., 2025)
Mutagen
CRISPR/Cas9
(Wang et al., 2025)
Progenitor genotype
Cytology
Description

4bp deletion within POLDIP2 that results in a premature stop codon in both POLDIP2 isoforms.

(Wang et al., 2025)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:5,468,153..5,468,156 [+]
Comment:

4bp deletion within POLDIP2 within the coding region in POLDIP2-RA and an intron in POLDIP2-RB.

(Wang et al., 2025)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      POLDIP2KO1
      poldip2KO1
      (Wang et al., 2025)
      poldip2Δ340-343
      (Wang et al., 2025)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)