A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG5703

General Information
SymbolDmel\CG5703SpeciesD. melanogaster
NameCG5703Annotation symbolCG5703
Feature typeprotein_coding_geneFlyBase IDFBgn0030853
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)XRecombination map
Cytogenetic map16B10-16B10Sequence locationX:17,526,122..17,527,539 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG5703 (FBgn0030853). It has the cytological map location 16B10. Its sequence location is X:17526122..17527539. Its molecular function is described as: NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity; NAD binding. It is involved in the biological process mitochondrial electron transport, NADH to ubiquinone. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
16B10-16B10  
Limits computationally determined from genome sequence between P{EP}bazEP1446 and P{EP}EP1464  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG5703 for information on other features
detailed view FBtr0074485 FBtr0074452 FBtr0074484 FBpp0074259 FBpp0074226 FBpp0074258 FBti0042764 FBti0075497
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG5703-RA
FBtr0074452
 NM_133000
  1061
  242
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG5703-PA  
FBpp0074226  
26.8  
242  
6.90  
  NP_573228
  AAF48745
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
NADH dehydrogenase (ubiquinone), 24 kDa subunit (IPR002023)
Thioredoxin fold (IPR012335)
Thioredoxin-like fold (IPR012336)
MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins
•
  • MTDROME05703
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AE003506
AAF48745
 
AI109684
 
AI133999
 
AI135666
 
AI258389
 
AI944401
 
AW941725
 
AY075322
AAL68189
 
BF496070
 
BG632504
 
BI214484
 
BI370603
 
BI482874
 
BI568819
 
BI570172
 
BI577763
 
BI582167
 
BI585424
 
BI586886
 
BI587111
 
BI587286
 
BI588723
 
BI611516
 
BI611781
 
BI611868
 
BI611904
 
BI611917
 
BI617148
 
BI622861
 
BI628777
 
CO318831
 
EC087628
 
EC216339
 
EC250351
 
RH01121
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    (Oliver, 2001.8.16)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Microarray Data
        Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)
        Untitled Document detailed view FBtr0074485 FBtr0074452 FBtr0074484
        AI109684
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 0 )
        For All Classical Alleles Show

        Allele of CG5703ClassMutagenStocksKnown lesion
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG5703ClassMutagenStocksKnown lesion
        CG5703GD117391 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD11739}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 5 )
        hide Molecular Function
        CV term
        Evidence
        References
        NAD binding
        inferred from electronic annotation with InterPro:IPR002023
        (FlyBase Curators et al., 2004-)
        NADH dehydrogenase (ubiquinone) activity
        inferred from sequence or structural similarity with UniProtKB:P04394
        (FlyBase, 1992-)
        NADH dehydrogenase activity
        inferred from sequence or structural similarity with UniProtKB:P19404
        (Sardiello et al., 2003.6.11)
        hide Biological Process
        CV term
        Evidence
        References
        mitochondrial electron transport, NADH to ubiquinone
        inferred from sequence or structural similarity with UniProtKB:P19404
        (Sardiello et al., 2003.6.11)
        hide Cellular Component
        CV term
        Evidence
        References
        mitochondrial respiratory chain complex I
        inferred from sequence or structural similarity with UniProtKB:P04394
        (FlyBase, 1992-)
        inferred from sequence or structural similarity with UniProtKB:P19404
        (Sardiello et al., 2003.6.11)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG5703 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 1 )
        VDRC
        v22194
        w1118; P{GD11739}v22194
        hide Genomic Clones ( 1 )
        hide cDNA Clones ( 28 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Source for merge of: CG5703 BEST:LP01573
        (Rana, 2004.7.8)
        Additional comments
        The CG6485 gene may have been derived from the CG5703 gene by retroposition.
        (Dai et al., 2006)
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        NADH dehydrogenase (ubiquinone), 24 kDa subunit (IPR002023)
        Thioredoxin fold (IPR012335)
        Thioredoxin-like fold (IPR012336)
        MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins
        •
        • MTDROME05703
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        InParanoid orthologs - Eukaryotic orthologs
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        University of Chicago Dev. Expression
        •
        hide Synonyms & Secondary IDs ( 2 )
        Reported As
        Symbol Synonym
        BEST:LP01573
         
        CG5703
        (Dai et al., 2006)
        Name Synonym
        CG5703
         
        Secondary FlyBase IDs
        • FBgn0046242
        hide References ( 11 )
        Research paper
        Dai et al., 2006, Gene 385: 96--102
        Retrogene movement within- and between-chromosomes in the evolution of Drosophila genomes. [FBrf0194437]
        McGraw et al., 2004, Curr. Biol. 14(16): 1509--1514
        Genes regulated by mating, sperm, or seminal proteins in mated female Drosophila melanogaster. [FBrf0180059]
        Supplementary material
        Giot et al., 2003, Science 302(5651):
        Tables S1 to S7. [FBrf0166452]
        Personal communication to FlyBase
        Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
        RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
        FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
        Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
        Rana, 2004.7.8, BLAST analysis.
        BLAST analysis. [FBrf0178762]
        Sardiello et al., 2003.6.11, MitoDrome: A database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion.
        MitoDrome: A database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion. [FBrf0159903]
        Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348).
        File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
        FlyBase analysis
        FlyBase, 1992-, FlyBase curation
        FlyBase curation. [FBrf0105495]
        Computer file
        BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
        Berkeley Drosophila Genome Project. [FBrf0125078]
        Curated genome annotation
        Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.]
        [Annotations performed at the Celera Jamboreee.] [FBrf0126651]