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General Information
Name
AUTOPHAGY-RELATED GENES
Species
D. melanogaster
Symbol
ATG
FlyBase ID
FBgg0000076
Date last reviewed
2014-06-19
Number of members
20
Description
Description
The Autophagy-related genes (Atg), characterized extensively in yeast, are a set of approximately twenty evolutionarily conserved genes required for autophagy. Autophagy (specifically, macroautophagy) is the process of bulk degradation of cytoplasmic material. It takes place by the assembly of a double membrane vesicle, the autophagosome, which delivers cargo to the lysosome for recycling. (Adapted from FBrf0219844 and FBrf020902).
Notes on Group
Source Material
The AUTOPHAGY-RELATED GENES Gene Group has been compiled by FlyBase curators using the following publication(s): Érdi et al., 2012, Zirin and Perrimon, 2010, and Kourtis and Tavernarakis, 2009.
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Other related group(s)
Members (20)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Autophagy-related 1
l(3)00305, Autophagy-specific gene 1, unc-51, DK-4, dAtg1
Autophagy-related 2
Autophagy-specific gene 2
Autophagy-related 3
Aut1, Autophagy-specific gene 3, dAtg3, Draut1
Autophagy-related 6
l(3)00096, beclin, Beclin1, Beclin-1, Autophagy-specific gene 6
Autophagy-related 7
autophagy-related protein 7, autophagy-related gene 7, Autophagy-specific gene 7, atg-7
Autophagy-related 8a
Atg8, LC3, Autophagy-specific gene 8a, DrAtg8a
Autophagy-related 8b
Atg8, Autophagy-specific gene 8b
Autophagy-related 12
Autophagy-specific gene 12
Autophagy-related 18a
Atg18, Autophagy-specific gene 18
Autophagy-related 18b
Atg18, l(2)k09410
External Data
Synonyms and Secondary IDs
Synonym(s)
ATG
AUTOPHAGY-RELATED GENES
Autophagy-specific genes
Atg
Atgr
Secondary FlyBase ID(s)
References (4)