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General Information
Name
AUTOPHAGY-RELATED GENES
Species
D. melanogaster
Symbol
ATG
FlyBase ID
FBgg0000076
Date last reviewed
2014-06-19
Number of members
20
Description
Description

The Autophagy-related genes (Atg), characterized extensively in yeast, are a set of approximately twenty evolutionarily conserved genes required for autophagy. Autophagy (specifically, macroautophagy) is the process of bulk degradation of cytoplasmic material. It takes place by the assembly of a double membrane vesicle, the autophagosome, which delivers cargo to the lysosome for recycling. (Adapted from FBrf0219844 and FBrf020902).

Notes on Group
Source Material
The AUTOPHAGY-RELATED GENES Gene Group has been compiled by FlyBase curators using the following publication(s): Érdi et al., 2012, Zirin and Perrimon, 2010, and Kourtis and Tavernarakis, 2009 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Other related group(s)
Members (20)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Autophagy-related 1
l(3)00305, Autophagy-specific gene 1, unc-51, DK-4, dAtg1
Autophagy-related 2
Autophagy-specific gene 2
Autophagy-related 3
Aut1, Draut1, Autophagy-specific gene 3, dAtg3
Autophagy-related 6
Beclin1, l(3)00096, beclin, DmAtg6, Autophagy-specific gene 6
Autophagy-related 7
dAtg7, autophagy-related gene 7, atg-7, autophagy-related protein 7, Autophagy-specific gene 7
Autophagy-related 8a
Atg8, LC3, Autophagy-specific gene 8a, Atg-8a, DrAtg8a
Autophagy-related 8b
Atg8, Autophagy-specific gene 8b
Autophagy-related 12
Autophagy-specific gene 12
Autophagy-related 18a
Atg18, Autophagy-specific gene 18
Autophagy-related 18b
Atg18, l(2)k09410
External Data
Synonyms and Secondary IDs
Synonym(s)
ATG
AUTOPHAGY-RELATED GENES
Autophagy-specific genes
Atg
Atgr
Secondary FlyBase ID(s)
References (4)