Gene Group: METHUSELAH-TYPE RECEPTORS

General Information

Name

METHUSELAH-TYPE RECEPTORS

Species

D. melanogaster

Symbol

MTH

FlyBase ID

FBgg0000134

Date last reviewed

2023-06-30

Number of members

Description

Methuselah GPCRs are Class B GPCRs, forming the B3 subgroup. The gene family's founding member methuselah (mth) was identified as a Drosophila GPCR involved in the modulation of life span and stress response. No counterpart for the methuselah gene family have been identified in vertebrates. (Adapted from FBrf0129744 and FBrf0218628).

Notes on Group

Source Material

The METHUSELAH-TYPE RECEPTORS Gene Group has been compiled using the following publication(s): de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, and Brody and Cravchik, 2000 .

Key Gene Ontology (GO) terms

Molecular Function

G protein-coupled receptor activity

Biological Process

G protein-coupled receptor signaling pathway

Cellular Component

plasma membrane

Related Gene Groups

Parent group(s)

CLASS B GPCRs

Members (16)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

mth

methuselah

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl1

methuselah-like 1

mist

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl2

methuselah-like 2

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl3

methuselah-like 3

BEST:GM02553

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl4

methuselah-like 4

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl5

methuselah-like 5

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl6

methuselah-like 6

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012)

mthl7

methuselah-like 7

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012)

mthl8

methuselah-like 8

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl9

methuselah-like 9

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl10

methuselah-like 10

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012, Harmar, 2001, Brody and Cravchik, 2000)

mthl11

methuselah-like 11

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012)

mthl12

methuselah-like 12

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012)

mthl13

methuselah-like 13

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012)

mthl14

methuselah-like 14

(de Mendoza et al., 2016, Hanlon and Andrew, 2015, Araújo et al., 2013, Li et al., 2013, Vogel et al., 2013, Patel et al., 2012)