Open Close
General Information
Name
WNTs
Species
D. melanogaster
Symbol
WNT
FlyBase ID
FBgg0000162
Date last reviewed
2013-02-22
Number of members
7
Description
Description
WNTs are evolutionarily conserved secreted Cys-rich glycoproteins, defined by sequence homology to the original members of the family - Wnt1 in mouse and wingless (wg) in Drosophila. They are extracellular ligands for members of the Frizzled family of receptors as well as other receptors. (Adapted from PMID:23151663).
Notes on Group
Source Material
The WNTs Gene Group has been compiled by FlyBase curators using the following publication(s): Mele and Johnson, 2019, Herr and Basler, 2012, and Llimargas and Lawrence, 2001 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
Members (7)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
wingless
Wnt, Sp, Wnt-1, Gla, spade
Wnt oncogene analog 2
DWnt-2, DWnt2, Wnt-2
Wnt oncogene analog 5
DWnt-3, DWnt5, DWnt3, Wnt3, Dwnt-5
wnt inhibitor of Dorsal
Wnt8, DWnt8, DWnt-8
External Data
Equivalent Group(s)
Other resource(s)

[The Wnt homepage](http://web.stanford.edu/group/nusselab/cgi-bin/wnt/drosophila)

Synonyms and Secondary IDs
Synonym(s)
WNT
WNTs
Wingless-type MMTV integration site
Wingless-type mouse mammary tumour virus integration site
DWnt
Secondary FlyBase ID(s)
References (4)