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General Information
Name
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1
Species
D. melanogaster
Symbol
BLOC1
FlyBase ID
FBgg0000185
Date last reviewed
2014-11-01
Number of members
8
Description
Description

The BLOC (biogenesis of lysosome-related organelles complex) complexes are required for the biogenesis of specialized organelles of the endosomal-lysosomal system. In mammalian cells, BLOC-1 localizes to early endosomes and facilitates protein trafficking to melanosomes in melanocytes. In D.mel, BLOC-1 has been shown to be involved in pigment granule biogenesis. (Adapted from FBrf0192474).

Notes on Group
Source Material
The BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1 Gene Group has been compiled by FlyBase curators using the following publication(s): Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, and Falcon-Perez et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
Cellular Component
Related Gene Groups
Members (8)
For all members:
External Data
Synonyms and Secondary IDs
Synonym(s)
BLOC1
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1
Biogenesis of lysosomal organelles complex-1
BLOC-1
Secondary FlyBase ID(s)
References (5)