Gene Group: CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS

General Information

Name

CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS

Species

D. melanogaster

Symbol

NPR

FlyBase ID

FBgg0000195

Date last reviewed

2023-06-30

Number of members

Description

The majority of neuropeptide/protein hormone GPCR belong to the Class A family of GPCRs. The secreted ligands for this subfamily include neuropeptides, peptide hormones and protein hormones. (Adapted from FBrf0195077).

Notes on Group

The CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS gene group contains neuropeptide and protein hormone-activated Class A GPCRs for which endogenous ligands have been identified and orphan receptors.

Source Material

The CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS Gene Group has been compiled using the following publication(s): Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hansen et al., 2011, Ida et al., 2011, Veenstra, 2009, Yapici et al., 2008, Garczynski et al., 2006, Hauser et al., 2006, Hauser et al., 2006, Jorgensen et al., 2006, Sudo et al., 2005, and Park et al., 2003 .

Key Gene Ontology (GO) terms

Molecular Function

G protein-coupled peptide receptor activity

Biological Process

G protein-coupled receptor signaling pathway

Cellular Component

plasma membrane

Related Gene Groups

Parent group(s)

CLASS A GPCRs

Other related group(s)

NEUROPEPTIDES

Members (44)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

AkhR

Adipokinetic hormone receptor

GRHR, Gonadotropin-releasing hormone receptor, DGRHR, AKH receptor, AKH-R

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

AstA-R1

Allatostatin A receptor 1

AlstR, AstAR1, DAR-1, EG:121E7.2, Galanin Receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

AstA-R2

Allatostatin A receptor 2

DAR-2, AR-2, DAR2, ASTR

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

AstC-R1

Allatostatin C receptor 1

star1, Drostar1, AstCR1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Veenstra, 2009, Hauser et al., 2006, Hauser et al., 2006)

AstC-R2

Allatostatin C receptor 2

AlCR2, AstCR2, lincRNA.610

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Veenstra, 2009, Hauser et al., 2006, Hauser et al., 2006)

CapaR

Capability receptor

capa receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)

CCAP-R

Crustacean cardioactive peptide receptor

CcapR, CCAP receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CCHa1-R

CCHamide-1 receptor

CCHa1r

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hansen et al., 2011, Hauser et al., 2006, Hauser et al., 2006)

CCHa2-R

CCHamide-2 receptor

CCHa2r, CCHamide-2 R

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hansen et al., 2011, Hauser et al., 2006, Hauser et al., 2006)

CCKLR-17D1

Cholecystokinin-like receptor at 17D1

CCKLR, DSK-R2, CCK-like receptor at 17D1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)

CCKLR-17D3

Cholecystokinin-like receptor at 17D3

DSK-R1, CCK-like receptor at 17D3

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG4313

EG:22E5.10

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG12290

lincRNA.S7704

(Hanlon and Andrew, 2015, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG13229

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)

CG13575

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG13995

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG30340

BG:BACR48G21.1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG32547

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CG33639

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

CNMaR

CNMamide Receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)

CrzR

Corazonin receptor

GRHRII, Crz-R, Crz receptor, DCR

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

ETHR

ETH receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)

FMRFaR

FMRFamide Receptor

FR, FMRFa-R, larval-opioid-receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)

Lgr1

Leucine-rich repeat-containing G protein-coupled receptor 1

DLGR1, TSH, FSH, LH/CG receptor, DLGR-1, Fsh

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Sudo et al., 2005)

Lgr3

Leucine-rich repeat-containing G protein-coupled receptor 3

DLGR3

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

Lgr4

Leucine-rich repeat-containing G protein-coupled receptor 4

DLGR4

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

Lkr

Leucokinin receptor

LK-R, Kinin receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

moody

EG:22E5.11, EP1631

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

MsR1

Myosuppressin receptor 1

DmsR-1, Dromyosuppressin receptor 1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)

MsR2

Myosuppressin receptor 2

DmsR-2, Dromyosuppressin receptor 2

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)

NPFR

Neuropeptide F receptor

NPFR1, NPF-R, DmNPFR1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

PK1-R

Pyrokinin 1 receptor

LstR, Pk1r

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)

PK2-R1

Pyrokinin 2 receptor 1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)

PK2-R2

Pyrokinin 2 receptor 2

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)

Proc-R

Proctolin receptor

ProcR

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

rickets

DLGR2, DLGR-2, lgr2, BG:DS00180.13

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Sudo et al., 2005)

RYa-R

RYamide receptor

NepYr, Neuropeptide Y receptor-like, PR4

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

SIFaR

SIFamide receptor

SIFR, SIF-R

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Jorgensen et al., 2006)

sNPF-R

short neuropeptide F receptor

sNPFR1, sNPFR, NPFR76F, sNPF receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Garczynski et al., 2006, Hauser et al., 2006, Hauser et al., 2006)

SPR

Sex peptide receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008)

TkR86C

Tachykinin-like receptor at 86C

Takr86C, NKD

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

TkR99D

Tachykinin-like receptor at 99D

DTKR, Takr99D, l(3)s2222, tachykinin receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

Tre1

Trapped in endoderm 1

sctt, Tre-1

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)

TrissinR

Trissin receptor

(Hanlon and Andrew, 2015, Vogel et al., 2013, Caers et al., 2012, Ida et al., 2011, Hauser et al., 2006, Hauser et al., 2006)

External Data

Equivalent Group(s)

Human Peptide receptors (HGNC)

Nematode Neuropeptide Receptors (WormBase)

Other resource(s)

Synonyms and Secondary IDs

Synonym(s)

NPR

CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS

Rhodopsin-like neuropeptide receptor

Rhodopsin-like protein hormone receptor

Family A neuropeptide receptor

Family A protein hormone receptor

Secondary FlyBase ID(s)

References (14)

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