FB2022_02, released March 29, 2022

Gene Group : CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS

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General Information
Name
CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS
Species
D. melanogaster
Symbol
NPR
FlyBase ID
FBgg0000195
Date last reviewed
2015-08-26
Number of members
44
Description
Description
The majority of neuropeptide/protein hormone GPCR belong to the Class A family of GPCRs. The secreted ligands for this subfamily include neuropeptides, peptide hormones and protein hormones. (Adapted from FBrf0195077).
Notes on Group

The CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS gene group contains neuropeptide and protein hormone-activated Class A GPCRs for which endogenous ligands have been identified and orphan receptors.

Source Material
The CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS Gene Group has been compiled by FlyBase curators using the following publication(s): Vogel et al., 2013, Caers et al., 2012, Hansen et al., 2011, Ida et al., 2011, Veenstra, 2009, Yapici et al., 2008, Garczynski et al., 2006, Hauser et al., 2006, Hauser et al., 2006, Jorgensen et al., 2006, Sudo et al., 2005, and Park et al., 2003 .
Key Gene Ontology (GO) terms
Molecular Function
G protein-coupled peptide receptor activity
Biological Process
G protein-coupled receptor signaling pathway
Cellular Component
integral component of plasma membrane
Related Gene Groups
Parent group(s)
CLASS A GPCRs
Other related group(s)
NEUROPEPTIDES
Members (44)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
AkhR
Adipokinetic hormone receptor
GRHR, DGRHR, Gonadotropin-releasing hormone receptor, AKH receptor
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
AstA-R1
Allatostatin A receptor 1
AlstR, AstAR1, DAR-1, EG:121E7.2, Galanin Receptor
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
AstA-R2
Allatostatin A receptor 2
DAR-2, AR-2, DAR2, ASTR
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
AstC-R1
Allatostatin C receptor 1
star1, Drostar1
(Vogel et al., 2013, Caers et al., 2012, Veenstra, 2009, Hauser et al., 2006, Hauser et al., 2006)
AstC-R2
Allatostatin C receptor 2
AlCR2, lincRNA.610
(Vogel et al., 2013, Caers et al., 2012, Veenstra, 2009, Hauser et al., 2006, Hauser et al., 2006)
CapaR
Capability receptor
capa receptor
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)
CCAP-R
Crustacean cardioactive peptide receptor
CcapR, CCAP receptor
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CCHa1-R
CCHamide-1 receptor
CCHa1r
(Vogel et al., 2013, Caers et al., 2012, Hansen et al., 2011, Hauser et al., 2006, Hauser et al., 2006)
CCHa2-R
CCHamide-2 receptor
CCHa2r, CCHamide-2 R
(Vogel et al., 2013, Caers et al., 2012, Hansen et al., 2011, Hauser et al., 2006, Hauser et al., 2006)
CCKLR-17D1
Cholecystokinin-like receptor at 17D1
CCK-like receptor at 17D1, CCKLR
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)
CCKLR-17D3
Cholecystokinin-like receptor at 17D3
DSK-R1, CCK-like receptor at 17D3
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG4313
EG:22E5.10
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG12290
lincRNA.S7704
(Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG13229
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)
CG13575
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG13995
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG30340
BG:BACR48G21.1
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG32547
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CG33639
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
CNMaR
CNMamide Receptor
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)
CrzR
Corazonin receptor
GRHRII, Crz receptor, DCR
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
ETHR
ETHR
ETH receptor
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)
FMRFaR
FMRFamide Receptor
FR, FMRFa-R, larval-opioid-receptor
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)
Lgr1
Leucine-rich repeat-containing G protein-coupled receptor 1
DLGR1, TSH, FSH, LH/CG receptor, Fsh, DLGR-1
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Sudo et al., 2005)
Lgr3
Leucine-rich repeat-containing G protein-coupled receptor 3
DLGR3
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
Lgr4
Leucine-rich repeat-containing G protein-coupled receptor 4
DLGR4
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
Lkr
Leucokinin receptor
LK-R, Kinin receptor
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
moody
moody
EG:22E5.11, EP1631
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
MsR1
Myosuppressin receptor 1
DmsR-1
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)
MsR2
Myosuppressin receptor 2
DmsR-2, Dromyosuppressin receptor 2
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006)
NPFR
Neuropeptide F receptor
NPFR1, NPF-R, DmNPFR1
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
PK1-R
Pyrokinin 1 receptor
LstR, Pk1r
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)
PK2-R1
Pyrokinin 2 receptor 1
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)
PK2-R2
Pyrokinin 2 receptor 2
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008, Hauser et al., 2006, Hauser et al., 2006, Park et al., 2003)
Proc-R
Proctolin receptor
ProcR
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
rk
rickets
DLGR2, lgr2, BG:DS00180.13, DLGR-2
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Sudo et al., 2005)
RYa-R
RYamide receptor
NepYr, PR4, Neuropeptide Y receptor-like
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
SIFaR
SIFamide receptor
SIFR
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006, Jorgensen et al., 2006)
sNPF-R
short neuropeptide F receptor
sNPFR1, sNPFR, NPFR76F, sNPF receptor
(Vogel et al., 2013, Caers et al., 2012, Garczynski et al., 2006, Hauser et al., 2006, Hauser et al., 2006)
SPR
Sex peptide receptor
(Vogel et al., 2013, Caers et al., 2012, Yapici et al., 2008)
TkR86C
Tachykinin-like receptor at 86C
Takr86C, NKD
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
TkR99D
Tachykinin-like receptor at 99D
DTKR, Takr99D, l(3)s2222, tachykinin receptor
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
Tre1
Trapped in endoderm 1
sctt, Tre-1
(Vogel et al., 2013, Caers et al., 2012, Hauser et al., 2006, Hauser et al., 2006)
TrissinR
Trissin receptor
(Vogel et al., 2013, Caers et al., 2012, Ida et al., 2011, Hauser et al., 2006, Hauser et al., 2006)
External Data
Synonyms and Secondary IDs
Synonym(s)
NPR
CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS
Rhodopsin-like neuropeptide receptor
Rhodopsin-like protein hormone receptor
Family A neuropeptide receptor
Family A protein hormone receptor
Secondary FlyBase ID(s)
References (13)