FB2025_02 , released April 17, 2025
Complex: CYTOPLASMIC LARGE RIBOSOMAL PROTEINS
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General Information
Name
CYTOPLASMIC LARGE RIBOSOMAL PROTEINS
Species
D. melanogaster
Symbol
RPL
FlyBase ID
FBgg0000200
Date last reviewed
2024-06-05
Number of members
54
Description
Description
Cytoplasmic ribosomes are found on the endoplasmic reticulum and in the cytoplasm. They translate all mRNAs produced from nuclear genes and perform the majority of cellular protein synthesis. Ribosomes are formed by two ribonucleoprotein subunits, large and small. The principle function of the large subunit is to bind tRNA during the synthesis of polypeptides. (Adapted from FBrf0205398).
Notes on Group

Cytoplasmic rRNAs are multicopy genes organised in tandem arrays (FBrf0202637). The large cytoplasmic rRNA genes can be found using SO:0002361 and associated with these records: 2SrRNA, 5SrRNA, 5.8SrRNA and 28SrRNA.

Source Material
The CYTOPLASMIC LARGE RIBOSOMAL PROTEINS Gene Group has been compiled using the following publication(s): Anger et al., 2013, Marygold et al., 2007, and Alonso and Santaren, 2006 .
Key Gene Ontology (GO) terms
Molecular Function
structural constituent of ribosome
Biological Process
translation
Cellular Component
cytosolic large ribosomal subunit
Related Gene Groups
Parent group(s)
CYTOPLASMIC RIBOSOMAL PROTEINS
Members (54)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)

[Ribosomal Protein Gene Database: D.MEL CYTOPLASMIC RIBOSOMAL PROTEINS](http://ribosome.med.miyazaki-u.ac.jp/rpg.cgi?mode=orglist&org=Drosophila%20melanogaster)

Synonyms and Secondary IDs
Synonym(s)
RPL
CYTOPLASMIC LARGE RIBOSOMAL PROTEINS
Large Cytoplasmic Ribosomal subunit
Large Cytoribosome
Large ribosome
Secondary FlyBase ID(s)
References (4)