FB2019_05, released Oct 15, 2019

Gene Group : CYCLIN DEPENDENT KINASES

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General Information
Name
CYCLIN DEPENDENT KINASES
Species
D. melanogaster
Symbol
CDK
FlyBase ID
FBgg0000239
Date last reviewed
2015-03-25
Number of members
12
Description
Description
Cyclin-dependent kinases (CDKs) are serine/threonine kinases whose activity depends on a regulatory cyclin subunit. (Adapted from PMID:25180339).
Notes on Group
Source Material
The CYCLIN DEPENDENT KINASES Gene Group has been compiled by FlyBase curators using the following publication(s): Sopko et al., 2014, Bartkowiak et al., 2010, Manning et al., 2002, Liu and Kipreos, 2000, and Morrison et al., 2000.
Key Gene Ontology (GO) terms
Molecular Function
cyclin-dependent protein serine/threonine kinase activity
Biological Process
protein phosphorylation
Cellular Component
Related Gene Groups
Parent group(s)
CMGC KINASES
Members (12)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cdc2rk
Cdc2-related kinase
Dcdrk
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk1
Cyclin-dependent kinase 1
cdc2, Dmcdc2
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk2
Cyclin-dependent kinase 2
cdc2c, Dmcdc2c, Cyclin E
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk4
Cyclin-dependent kinase 4
Cdk4/6, l(2)05428, dCdk4, l(2)s4639, 8-6
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk5
Cyclin-dependent kinase 5
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk7
Cyclin-dependent kinase 7
Mo15, DmCdk7, DmMO15
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk8
Cyclin-dependent kinase 8
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk9
Cyclin-dependent kinase 9
P-TEFb, Positive transcription elongation factor b
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Cdk12
Cyclin-dependent kinase 12
AC017581
(Sopko et al., 2014, Bartkowiak et al., 2010, Manning et al., 2002, Liu and Kipreos, 2000)
CG6800
AC014407
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Eip63E
Ecdysone-induced protein 63E
L63, PFTAIRE, cdc2-63E
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
Pitslre
Pitslre
cdk11, group 3
(Sopko et al., 2014, Manning et al., 2002, Liu and Kipreos, 2000, Morrison et al., 2000)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
CDK
CYCLIN DEPENDENT KINASES
CDKs
Secondary FlyBase ID(s)
References (6)