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General Information
Name
DUAL SPECIFICITY PHOSPHATASES
Species
D. melanogaster
Symbol
DSP
FlyBase ID
FBgg0000265
Date last reviewed
2015-06-08
Number of members
23
Description
Description

Dual Specificity Phosphatases (DSP) can dephosphorylate both tyrosine and serine/threonine residues. Additionally, DSPs may target a much larger and diverse set of substrates, including phosphoinositide lipids, RNA 5'-triphosphate and carbohydrates. (Adapted from FBrf0227974).

Notes on Group

CG14411, CG5026 and Sbf are predicted to be pseudophosphatases in FBrf0227974.

CG3632, mtm, CG3530, Pten and Plip are also members of the PHOSPHATIDYLINOSITOL PHOSPHATE AND INOSITOL PHOSPHATE PHOSPHATASES gene group.

Source Material
The DUAL SPECIFICITY PHOSPHATASES Gene Group has been compiled by FlyBase curators using the following publication(s): Hatzihristidis et al., 2015, Morrison et al., 2000, and Walchli et al., 2000 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Related Gene Groups
Members (23)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Egg-derived tyrosine phosphatase
MAP kinase-specific phosphatase
DMKP
Mitogen-activated protein kinase phosphatase 3
DMKP-3, MAP Kinase Phosphatase 3
Protein tyrosine phosphatase, mitochondrial 1
Plip
SET domain binding factor
Sbf1
string
cdc25, cdc25string, l(3)01235, string/cdc25, Cdc25stg
twine
Cdc25, twn, mat(2)synHB5, l(2)35Fh, mat(2)synHB5
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
DSP
DUAL SPECIFICITY PHOSPHATASES
Dual specificity protein phosphatases
DUSP
Secondary FlyBase ID(s)
References (4)