FB2025_01 , released February 20, 2025
Complex: PHO REPRESSIVE COMPLEX - PHO VARIANT
Open Close
General Information
Name
PHO REPRESSIVE COMPLEX - PHO VARIANT
Species
D. melanogaster
Symbol
PHORC
FlyBase ID
FBgg0000289
Date last reviewed
2024-01-25
Number of members
2
Description
Description
In Drosophila, the Pho repressive complex (PhoRC) can bind Polycomb Response Elements (PREs) and recruit Polycomb repressive complexes. (Adapted from FBrf0190547 and FBrf0220020).
Notes on Group

Sfmbt can form stable dimeric complexes with pho or phol. (FBrf0190547).

Source Material
The PHO REPRESSIVE COMPLEX - PHO VARIANT Gene Group has been compiled using the following publication(s): Kassis et al., 2017, Lanzuolo and Orlando, 2012, and Klymenko et al., 2006 .
Key Gene Ontology (GO) terms
Molecular Function
chromatin binding
Biological Process
heterochromatin formation
Cellular Component
PcG protein complex
Related Gene Groups
Parent group(s)
POLYCOMB GROUP COMPLEXES
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
pho
pleiohomeotic
l(4)29, YY1, Pleohomeotic, l(4)BU-2, l(4)102EFc
(Kassis et al., 2017, Lanzuolo and Orlando, 2012, Klymenko et al., 2006)
Sfmbt
Scm-related gene containing four mbt domains
dSfmbt
(Kassis et al., 2017, Lanzuolo and Orlando, 2012, Klymenko et al., 2006)
External Data
Synonyms and Secondary IDs
Synonym(s)
PHORC
PhoRC complex
PhoRC complex 1
Pho-repressive complex
Pho-RC
PHO REPRESSIVE COMPLEX - PHO VARIANT
PHO REPRESSIVE COMPLEX
Secondary FlyBase ID(s)
References (4)