FB2025_01 , released February 20, 2025
Complex: COMPASS COMPLEX
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General Information
Name
COMPASS COMPLEX
Species
D. melanogaster
Symbol
COMP
FlyBase ID
FBgg0000296
Date last reviewed
Number of members
8
Description
Description
COMPASS is a histone H3K4 methyltransferase complex thought to be responsible for the bulk of the histone H3K4 di- and trimethylation in Drosophila. (Adapted from FBrf0216343).
Notes on Group
Source Material
The COMPASS COMPLEX Gene Group has been compiled using the following publication(s): Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, and Schuettengruber et al., 2011 .
Key Gene Ontology (GO) terms
Molecular Function
histone H3K4 methyltransferase activity
Biological Process
chromatin remodeling
Cellular Component
Set1C/COMPASS complex
Related Gene Groups
Parent group(s)
COMPASS-TYPE COMPLEXES
Members (8)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ash2
absent, small, or homeotic discs 2
ash-2
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
Cfp1
CXXC finger protein 1
CXXC1
(Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
Dpy-30L1
Dpy-30-like 1
Dpy30
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
Hcf
Host cell factor
dHCF, Hcf1, dHcf1
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
Rbbp5
Retinoblastoma binding protein 5
dRbbp5
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
Set1
SET domain containing 1
dSet1
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
Wdr82
WD repeat domain 82
dWdr82
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
wds
will die slowly
zw8, l(1)zw8, zw-8, EG:BACR25B3.7, l(1)3Ad
(Piunti and Shilatifard, 2016, Shilatifard, 2012, Mohan et al., 2011, Schuettengruber et al., 2011)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
COMP
COMPASS COMPLEX
SET1C complex
Complex proteins associated with Set1 complex
Set1/COMPASS
dSet1
Set1
Secondary FlyBase ID(s)
References (5)