FB2025_01 , released February 20, 2025
Gene Group: RHO GTPASES
Open Close
General Information
Name
RHO GTPASES
Species
D. melanogaster
Symbol
RHO
FlyBase ID
FBgg0000320
Date last reviewed
2015-08-06
Number of members
9
Description
Description
Rho (Ras Homologous) GTPases are members of the Ras superfamily of small GTPases. They are best characterized for their roles in regulating actin organization. (Adapted from PMID:15731001).
Notes on Group

Miro is an atypical member of the Rho family, possessing two GTPase domains (FBrf0182799).

Source Material
The RHO GTPASES Gene Group has been compiled using the following publication(s): Neisch et al., 2013, Rojas et al., 2012, and Colicelli, 2004 .
Key Gene Ontology (GO) terms
Molecular Function
GTPase activity
Biological Process
small GTPase-mediated signal transduction
Cellular Component
Related Gene Groups
Parent group(s)
RAS GTPASE SUPERFAMILY
Other related group(s)
RHO GTPASE ACTIVATING PROTEINS
RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS
Members (9)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cdc42
Cell division cycle 42
Dcdc42, DmCDC42
(Neisch et al., 2013, Rojas et al., 2012, Colicelli, 2004)
Miro
Mitochondrial Rho
dmiro
(Rojas et al., 2012, Colicelli, 2004)
Mtl
Mig-2-like
Rac, Rac GTPase
(Neisch et al., 2013, Colicelli, 2004)
Rac1
Rac1
Rac, Drac1, Rac GTPase, Drac, D-Rac1
(Neisch et al., 2013, Rojas et al., 2012, Colicelli, 2004)
Rac2
Rac2
Rac, Rac1, Drac2, Rac GTPase, D-Rac2
(Neisch et al., 2013, Rojas et al., 2012, Colicelli, 2004)
Rho1
Rho1
RhoA, Rho, Rho GTPase, Rho kinase, DrhoA
(Neisch et al., 2013, Rojas et al., 2012, Colicelli, 2004)
RhoBTB
Rho-related BTB domain containing
RhoGTPase, RhoX
(Neisch et al., 2013, Rojas et al., 2012, Colicelli, 2004)
RhoL
Rho-like
Mes1, Drac3, DRhoL
(Neisch et al., 2013, Colicelli, 2004)
RhoU
RhoU
(Neisch et al., 2013, Colicelli, 2004)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
RHO
RHO GTPASES
Ras homologous GTPases
Secondary FlyBase ID(s)
References (4)