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General Information
Name
TRANSCRIPTION FACTOR II H - CORE COMPLEX
Species
D. melanogaster
Symbol
TFIIH-C
FlyBase ID
FBgg0000357
Date last reviewed
2015-09-29
Number of members
7
Description
Description

The general transcription factor complex Transcription factor II H (TFIIH) is required in RNA pol II transcription at initiation, promoter escape, early elongation steps and transcription re-initiation after polymerase pausing. TFIIH can be divided into two subcomplexes: core and cyclin-dependent protein kinase-activating kinase (CAK). The core complex contains an ATP-dependent DNA helicase activity required for promoter DNA opening and nucleotide excision repair (NER). (Adapted from PMID:25693126 and PMID:21592869).

Notes on Group
Source Material
The TRANSCRIPTION FACTOR II H - CORE COMPLEX Gene Group has been compiled by FlyBase curators using the following publication(s): Stettler et al., 2015, Aguilar-Fuentes et al., 2008, Gutierrez et al., 2004, and Aoyagi and Wassarman, 2000 .
Key Gene Ontology (GO) terms
Related Gene Groups
Members (7)
For all members:
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
TFIIH-C
TRANSCRIPTION FACTOR II H - CORE COMPLEX
TF-IIH core
Secondary FlyBase ID(s)
References (5)