FB2025_01 , released February 20, 2025
Complex: DYNACTIN COMPLEX
Open Close
General Information
Name
DYNACTIN COMPLEX
Species
D. melanogaster
Symbol
DYNA-C
FlyBase ID
FBgg0000376
Date last reviewed
Number of members
11
Description
Description
Dynactin is a large 1.2 MDa multisubunit protein complex that associates with the cytoplasmic dynein complex to drive microtubule-based transport. (Adapted from PMID:15473859 and PMID:25751425).
Notes on Group

In Drosophila there are two dynactin1/p150Glued genes DCTN1-p150 and CG9279 resulting from a gene duplication event (FBrf0207657, FBrf0229712).

Source Material
The DYNACTIN COMPLEX Gene Group has been compiled using the following publication(s): Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, and Goldstein and Gunawardena, 2000 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
microtubule-based movement
Cellular Component
dynactin complex
Related Gene Groups
Other related group(s)
DYNEIN SUBUNITS
Members (11)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Arp1
Actin-related protein 1
Arp87C, gridlock, grid, Actin-related protein 87C
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Eckley and Schroer, 2003)
Arp10
Actin-related protein 10
Arp11
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Eckley and Schroer, 2003)
cpa
capping protein alpha
miro, Cap1, Capping Protein, Capping protein α
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
cpb
capping protein beta
capping protein β, capping protein, Cap2, CapZ, burned
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Eckley and Schroer, 2003)
DCTN1-p150
Dynactin 1, p150 subunit
Glued, Gl, p150Glued, p150, dynactin
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
DCTN2-p50
Dynactin 2, p50 subunit
Dmn, dynamitin, p50, p50-dynamitin, DCTN2
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
DCTN3-p24
Dynactin 3, p24 subunit
l(2)06496, DCTN3
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
DCTN4-p62
Dynactin 4, p62 subunit
p62, DCTN4
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
DCTN5-p25
Dynactin 5, p25 subunit
l(2)35Bf, l(2)br2, dyn-p25, p25, BG:DS00929.1
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
DCTN6-p27
Dynactin 6, p27 subunit
l(2)37Ce, DCTN6, l(2)E62, Ce
(Butzlaff et al., 2015, Kollmar, 2015.9.21, Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Eckley and Schroer, 2003, Goldstein and Gunawardena, 2000)
Dred
Dctn1-related
(Hammesfahr and Kollmar, 2012, Kollmar and Odronitz, 2006, Goldstein and Gunawardena, 2000)
External Data
Synonyms and Secondary IDs
Synonym(s)
DYNA-C
DYNACTIN COMPLEX
Dynein activator complex
DCTN
Secondary FlyBase ID(s)
References (7)