FB2025_01 , released February 20, 2025
Gene Group: DYNEIN LIGHT INTERMEDIATE CHAINS
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General Information
Name
DYNEIN LIGHT INTERMEDIATE CHAINS
Species
D. melanogaster
Symbol
DYN-LIC
FlyBase ID
FBgg0000383
Date last reviewed
2016-01-21
Number of members
2
Description
Description
Dyneins are minus end-directed microtubule motor protein complexes. Dynein light intermediate chains (LIC) are subunits of dynein complexes. In cytoplasmic dynein complexes, dynein LIC binds as a dimer to dynein heavy chains and is involved in cargo attachment. (Adapted from PMID:19935668 and FBrf0206979).
Notes on Group

Although Dlic has a P-loop/G domain, it probably does not possess GTPase activity. Human cytoplasmic light intermediate chain 1 (DYNC1LI1) preferentially binds GDP (PMID:25272277).

Source Material
The DYNEIN LIGHT INTERMEDIATE CHAINS Gene Group has been compiled using the following publication(s): Mische et al., 2008 and Pfister et al., 2006 .
Key Gene Ontology (GO) terms
Molecular Function
dynein heavy chain binding
Biological Process
microtubule-based movement
Cellular Component
dynein complex
Related Gene Groups
Parent group(s)
DYNEIN SUBUNITS
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG3769
(Mische et al., 2008, Pfister et al., 2006)
Dlic
Dynein light intermediate chain
Dlic2, l(1)G0065, dandelion clock, l(1)G0190
(Mische et al., 2008, Pfister et al., 2006)
External Data
Synonyms and Secondary IDs
Synonym(s)
DYN-LIC
DYNEIN LIGHT INTERMEDIATE CHAINS
DLIC
Secondary FlyBase ID(s)
References (3)