Dyneins are minus end-directed microtubule motor protein complexes. Axonemal dynein complexes interact with adjacent microtubules in the axoneme. Coordinated binding and release of the axonemal dyneins slide the microtubules relative to each other causing the axoneme to bend driving ciliary and flagellar motion. Axonemal dynein intermediate chains are subunits of axonemal dynein complexes that mediate movement of the axoneme. Axonemal inner arm dynein intermediate chains are subunits of inner arm axonemal dynein. (Adapted from PMID:24064538).