FB2025_01 , released February 20, 2025
Gene Group: MITOCHONDRIAL COMPLEX V - F1 SUBUNITS
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General Information
Name
MITOCHONDRIAL COMPLEX V - F1 SUBUNITS
Species
D. melanogaster
Symbol
MCV-F1
FlyBase ID
FBgg0000483
Date last reviewed
2024-09-16
Number of members
7
Description
Description
Mitochondrial ATP synthase (Complex V) synthesizes ATP from ADP and inorganic phosphate using the energy provided by the proton electrochemical gradient across the inner mitochondrial membrane. It consists of two structural domains: the F[[1]] sector, a soluble portion situated in the mitochondrial matrix, and the F[[0]] sector, which spans the inner mitochondrial membrane. The F[[1]] sector is composed of three copies each of subunits alpha and beta, which form the catalytic core that synthesizes ATP, and one each of subunits gamma, delta and epsilon, which constitute the central stalk. When uncoupled from the mitochondria this sector acts as an ATPase. (Adapted from PMID:21874297).
Notes on Group
Source Material
The MITOCHONDRIAL COMPLEX V - F1 SUBUNITS Gene Group has been compiled using the following publication(s): Sawyer et al., 2017, Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, and Tripoli et al., 2005 .
Key Gene Ontology (GO) terms
Molecular Function
proton-transporting ATP synthase activity, rotational mechanism
Biological Process
proton motive force-driven ATP synthesis
Cellular Component
mitochondrial inner membrane
proton-transporting ATP synthase complex
Related Gene Groups
Parent group(s)
MITOCHONDRIAL COMPLEX V SUBUNITS
Component group(s)
MITOCHONDRIAL COMPLEX V - ATP SYNTHASES
MITOCHONDRIAL COMPLEX V - CENTRAL STALK
Members (7)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
MITOCHONDRIAL COMPLEX V - ATP SYNTHASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ATPsynβ
ATP synthase, β subunit
ATPsyn-beta, ATPsyn-β, ATP synthase-β, ATP synthase β subunit, ATPB
(FlyBase, 2017-, Porcelli and Marygold, 2014.9.16, Tripoli et al., 2005)
ATPsynβL
ATP synthase, β subunit-like
ms(3)72Dt
(FlyBase, 2017-, Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, Tripoli et al., 2005)
blw
bellwether
ATP5A, ATPsyn-α, Complex Vα, C-V-α, ATPsynα
(FlyBase, 2017-, Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, Tripoli et al., 2005)
MITOCHONDRIAL COMPLEX V - CENTRAL STALK
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ATPsynδ
ATP synthase, δ subunit
l(1)G0230, lethal (1) G0230, l (1) G0230
(Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, Tripoli et al., 2005)
ATPsynεL
ATP synthase, ε subunit-like
(Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, Tripoli et al., 2005)
ATPsynγ
ATP synthase, γ subunit
ATPsyn-gamma, ATPsyn-γ, ATP synthase-gamma chain
(Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, Tripoli et al., 2005)
sun
stunted
ATP synthase epsilon chain
(Porcelli and Marygold, 2014.9.16, Caggese et al., 2006, Tripoli et al., 2005)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
F1 sector
F1 ATP synthase domain
F1-ATPSYN
MITOCHONDRIAL COMPLEX V - F1 SUBUNITS
MITOCHONDRIAL F1 ATP SYNTHASE COMPLEX SUBUNITS
MCV-F1
Secondary FlyBase ID(s)
References (6)