FB2025_01 , released February 20, 2025
Gene Group: HEAT SHOCK PROTEIN 60 CHAPERONINS
Open Close
General Information
Name
HEAT SHOCK PROTEIN 60 CHAPERONINS
Species
D. melanogaster
Symbol
HSP60
FlyBase ID
FBgg0000503
Date last reviewed
2016-05-04
Number of members
12
Description
Description
The Heat Shock Protein 60 (Hsp60) family of chaperonins assist in the correct folding of newly synthesized or stress denatured proteins in an ATP-dependent manner. They are divided into two groups (I and II) that are structurally similar and quite diverse in sequence. Chaperonins form a large cage-like structure composed of two rings. (Adapted from FBrf0232269).
Notes on Group
Source Material
The HEAT SHOCK PROTEIN 60 CHAPERONINS Gene Group has been compiled using the following publication(s): Morrow et al., 2016, Monzo et al., 2010, Arya et al., 2007, and Sarkar and Lakhotia, 2005 .
Key Gene Ontology (GO) terms
Molecular Function
ATP-dependent protein folding chaperone
Biological Process
protein folding
Cellular Component
Related Gene Groups
Parent group(s)
ATP-DEPENDENT PROTEIN FOLDING CHAPERONES
HEAT SHOCK PROTEINS
Component group(s)
CHAPERONIN CONTAINING TCP-1 COMPLEX
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I
Members (12)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
CHAPERONIN CONTAINING TCP-1 COMPLEX
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CCT1
Chaperonin containing TCP1 subunit 1
T-cp1, Tcp1-like, T-cpl, Tcp1, TCP1α
(Monzo et al., 2010)
CCT2
Chaperonin containing TCP1 subunit 2
(Monzo et al., 2010)
CCT3
Chaperonin containing TCP1 subunit 3
Cctgamma, Cctγ, Cctg, vine, Y
(Monzo et al., 2010)
CCT4
Chaperonin containing TCP1 subunit 4
(Monzo et al., 2010)
CCT5
Chaperonin containing TCP1 subunit 5
l(2)06444, T-complex Chaperonin 5
(Monzo et al., 2010)
CCT6
Chaperonin containing TCP1 subunit 6
Tcp-1zeta, l(1)G0057, Tcp-1ζ, lethal (1) G0022, l(1)G0027
(Monzo et al., 2010)
CCT7
Chaperonin containing TCP1 subunit 7
Tcp-1eta, Tcp-1η
(Monzo et al., 2010)
CCT8
Chaperonin containing TCP1 subunit 8
(Monzo et al., 2010)
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Hsp60A
Heat shock protein 60A
Hsp60, l(1)BP5, heat shock protein 60, 12, Hsp 60
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60B
Heat shock protein 60B
ms(2)21D, Hsp64, Heat shock protein 60 related
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60C
Heat shock protein 60C
Hsp64
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60D
Heat shock protein 60D
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
External Data
Equivalent Group(s)
Other resource(s)

[Heat shock protein information resource:Hsp60 ](http://pdslab.biochem.iisc.ernet.in/hspir/hsp60.php)

Synonyms and Secondary IDs
Synonym(s)
HSP60
HEAT SHOCK PROTEIN 60 CHAPERONINS
Chaperonins
HSP60 Chaperones
60 kDa chaperonin family
Heat shock proteins 60kDa
Secondary FlyBase ID(s)
References (5)