The small Heat Shock Protein (sHSP) family is characterized by the presence of an α-crystallin domain. sHSPs play a crucial role in protein folding. Most sHSPs have the ability to prevent protein aggregation and to maintain substrate proteins in a refoldable state. (Adapted from FBrf0228040 and FBrf0231212).
[Heat shock protein information resource:sHsp ](http://pdslab.biochem.iisc.ernet.in/hspir/shsp.php)