FB2020_05, released Oct 14, 2020

Gene Group : SMALL HEAT SHOCK PROTEINS

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General Information
Name
SMALL HEAT SHOCK PROTEINS
Species
D. melanogaster
Symbol
S-HSP
FlyBase ID
FBgg0000507
Date last reviewed
2016-04-21
Number of members
11
Description
Description

The small Heat Shock Protein (sHSP) family is characterized by the presence of an α-crystallin domain. sHSPs play a crucial role in protein folding. Most sHSPs have the ability to prevent protein aggregation and to maintain substrate proteins in a refoldable state. (Adapted from FBrf0228040 and FBrf0231212).

Notes on Group

FBrf0231212 reported that heat shock stimulates the transcription of all sHSPs with the exception of CG14207 and CG13133 in S2 cells.

Source Material
The SMALL HEAT SHOCK PROTEINS Gene Group has been compiled by FlyBase curators using the following publication(s): Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, and Michaud et al., 2002 .
Key Gene Ontology (GO) terms
Molecular Function
unfolded protein binding
Biological Process
response to heat
protein folding
chaperone-mediated protein folding
Cellular Component
Related Gene Groups
Parent group(s)
HEAT SHOCK PROTEINS
Members (11)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG4461
Hsp20
(Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
CG7409
(Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
CG13133
(Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
CG14207
HspB8
(Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
Hsp22
Heat shock protein 22
DmHsp22
(Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp23
Heat shock protein 23
DmHsp23, 23
(Vos et al., 2016, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp26
Heat shock protein 26
DmHsp26, Hsp 26, 26
(Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp27
Heat shock protein 27
Hsp28, Dhsp27, DmHsp27, Hsp 27
(Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp67Ba
Heat shock gene 67Ba
gene 1, gene1
(Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Michaud et al., 2002)
Hsp67Bc
Heat shock gene 67Bc
gene 3
(Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Michaud et al., 2002)
l(2)efl
lethal (2) essential for life
CryAB
(Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
External Data
Equivalent Group(s)
Other resource(s)

[Heat shock protein information resource:sHsp ](http://pdslab.biochem.iisc.ernet.in/hspir/shsp.php)

Synonyms and Secondary IDs
Synonym(s)
S-HSP
SMALL HEAT SHOCK PROTEINS
sHSP
Secondary FlyBase ID(s)
References (6)