General Information
D. melanogaster
FlyBase ID
Date last reviewed
Number of members
Potassium channels (KCN) are transmembrane channels specific for potassium. This ubiquitous family of membrane proteins are present in both excitable and non-excitable cells. They play critical roles in many processes such as signaling, neurotransmission, cardiac rhythm and electrolyte transport. (Adapted from PMID:11121510).
Notes on Group
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (27)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Inwardly rectifying potassium channel 1
Ir, Dm_3R:100349, Dm_3R:100326
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
small conductance calcium-activated potassium channel
slowpoke 2
Dm_2R:24438, Dm_2R:24301
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Dm_X:51771, lincRNA.975, Hyperkinetic
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Secondary FlyBase ID(s)
References (14)
Research paper
Hu et al., 2015, PLoS Biol. 13(4): e1002115
Ih channels control feedback regulation from amacrine cells to photoreceptors. [FBrf0227998]
Wu et al., 2015, Am. J. Physiol. R., Regul. Integr. Comp. Physiol. 309(7): R747--R756
Two inwardly rectifying potassium channels, Irk1 and Irk2, play redundant roles in Drosophila renal tubule function. [FBrf0229719]
Huang et al., 2014, J. Mol. Neurosci. 53(1): 41--49
Evolutionary analysis of voltage-gated potassium channels by bayes method. [FBrf0224790]
Chintapalli et al., 2013, BMC Genomics 14: 518
Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia. [FBrf0222336]
Chen and Wang, 2012, Sci. China Life Sci. 55(1): 2--7
Functional study of hyperpolarization activated channel (I ( h )) in Drosophila behavior. [FBrf0217396]
Döring et al., 2006, Europ. J. Neurosci. 24(8): 2264--2274
Novel Drosophila two-pore domain K+ channels: rescue of channel function by heteromeric assembly. [FBrf0192007]
Gisselmann et al., 2005, Insect Biochem. Mol. Biol. 35(5): 505--514
Variants of the Drosophila melanogaster I(h)-channel are generated by different splicing. [FBrf0184031]
McCormack, 2003, Genome Biol. 4(9): R58
Comparison of K+-channel genes within the genomes of Anopheles gambiae and Drosophila melanogaster. [FBrf0162165]
Doring et al., 2002, J. Biol. Chem. 277(28): 25554--25561
Inwardly rectifying K+ (Kir) channels in Drosophila. A crucial role of cellular milieu factors for Kir channel function. [FBrf0150787]
FlyBase analysis
FlyBase, 2014-, FlyBase Gene Group information.
FlyBase Gene Group information. [FBrf0225556]
Frolov et al., 2012, J. Neurogenet. 26(3-4): 275--290
Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives. [FBrf0220575]
Luan and Li, 2012, Sheng Li Xue Bao 64(5): 515--519
Inwardly rectifying potassium channels in Drosophila. [FBrf0219718]
Salkoff et al., 2006, Nat. Rev. Neurosci. 7(12): 921--931
High-conductance potassium channels of the SLO family. [FBrf0193525]
Buckingham et al., 2005, Trends Pharmacol. Sci. 26(7): 361--367
Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms. [FBrf0188365]