General Information
Name
POTASSIUM CHANNEL SUBUNITS
Species
D. melanogaster
Symbol
KCN
FlyBase ID
FBgg0000512
Date last reviewed
2016-05-11
Number of members
27
Description
Description
Potassium channels (KCN) are transmembrane channels specific for potassium. This ubiquitous family of membrane proteins are present in both excitable and non-excitable cells. They play critical roles in many processes such as signaling, neurotransmission, cardiac rhythm and electrolyte transport. (Adapted from PMID:11121510).
Notes on Group
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (27)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Inwardly rectifying potassium channel 1
Ir, Dm_3R:100349, Dm_3R:100326
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
small conductance calcium-activated potassium channel
dSK
slowpoke 2
Dm_2R:24438, Dm_2R:24301
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Hyperkinetic
Dm_X:51771, lincRNA.975, Hyperkinetic
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
KCN
POTASSIUM CHANNEL SUBUNITS
Secondary FlyBase ID(s)
References (14)
Research paper
Hu et al., 2015, PLoS Biol. 13(4): e1002115
Ih channels control feedback regulation from amacrine cells to photoreceptors. [FBrf0227998]
Wu et al., 2015, Am. J. Physiol. R., Regul. Integr. Comp. Physiol. 309(7): R747--R756
Two inwardly rectifying potassium channels, Irk1 and Irk2, play redundant roles in Drosophila renal tubule function. [FBrf0229719]
Huang et al., 2014, J. Mol. Neurosci. 53(1): 41--49
Evolutionary analysis of voltage-gated potassium channels by bayes method. [FBrf0224790]
Chintapalli et al., 2013, BMC Genomics 14: 518
Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia. [FBrf0222336]
Chen and Wang, 2012, Sci. China Life Sci. 55(1): 2--7
Functional study of hyperpolarization activated channel (I ( h )) in Drosophila behavior. [FBrf0217396]
Döring et al., 2006, Europ. J. Neurosci. 24(8): 2264--2274
Novel Drosophila two-pore domain K+ channels: rescue of channel function by heteromeric assembly. [FBrf0192007]
Gisselmann et al., 2005, Insect Biochem. Mol. Biol. 35(5): 505--514
Variants of the Drosophila melanogaster I(h)-channel are generated by different splicing. [FBrf0184031]
McCormack, 2003, Genome Biol. 4(9): R58
Comparison of K+-channel genes within the genomes of Anopheles gambiae and Drosophila melanogaster. [FBrf0162165]
Doring et al., 2002, J. Biol. Chem. 277(28): 25554--25561
Inwardly rectifying K+ (Kir) channels in Drosophila. A crucial role of cellular milieu factors for Kir channel function. [FBrf0150787]
FlyBase analysis
FlyBase, 2014-, FlyBase Gene Group information.
FlyBase Gene Group information. [FBrf0225556]
Review
Frolov et al., 2012, J. Neurogenet. 26(3-4): 275--290
Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives. [FBrf0220575]
Luan and Li, 2012, Sheng Li Xue Bao 64(5): 515--519
Inwardly rectifying potassium channels in Drosophila. [FBrf0219718]
Salkoff et al., 2006, Nat. Rev. Neurosci. 7(12): 921--931
High-conductance potassium channels of the SLO family. [FBrf0193525]
Buckingham et al., 2005, Trends Pharmacol. Sci. 26(7): 361--367
Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms. [FBrf0188365]