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General Information
Name
SPLICEOSOME COMPLEX A
Species
D. melanogaster
Symbol
SPL-C-A
FlyBase ID
FBgg0000535
Date last reviewed
2016-09-05
Number of members
50
Description
Description

Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).

Notes on Group
Source Material
The SPLICEOSOME COMPLEX A Gene Group has been compiled by FlyBase curators using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (50)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
DEAH-box helicase 15
half pint
pUf68, pUbsf, DPUF68, poly U binding factor 68kD, PUF60
Heterogeneous nuclear ribonucleoprotein at 87F
hrp36, P11, hnRNPA1, Hrb87Fa, hnRNPA2
Heterogeneous nuclear ribonucleoprotein at 98DE
hrp38
noisette
SF3A3, l(3)j3E7
PHD finger protein 5a
SR-related CTD associated factor 6
BP1040, BP1047
Splicing factor 3a subunit 1
Splicing factor 3a subunit 2
Splicing factor 3b subunit 1
Splicing factor 3b subunit 2
Splicing factor 3b subunit 3
Splicing factor 3b subunit 5
Splicing factor 3b subunit 6
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmD1
snRNP69D
Small ribonucleoprotein particle protein SmD2
snRNP2
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
Small ribonucleoprotein particle protein SmE
snRNPE
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
sans fille
fs(1)1621, fs(1)A1621, liz, SNF/D25, splicing necessary factor
small nuclear RNA U1 at 21D
U1, U1 snRNA, snRNA:U1, U1snRNA, U1-21.1
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1snRNA, U1:82Eb, U1-82.3
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, U1snRNA
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1snRNA, U1:95Cb, snRNA:U1
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cc
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, U2:14B, snRNA:U2
small nuclear RNA U2 at 34AB a
U2 snRNA, U2, dU2, U2-131A, U2:34ABa
small nuclear RNA U2 at 34AB b
U2 snRNA, U2, dU2, snRNA:U2, U2:34ABb
small nuclear RNA U2 at 34AB c
U2 snRNA, U2, dU2, snRNA:U2
small nuclear RNA U2 at 38AB a
U2 snRNA, U2, dU2, U2:38ABa, U2-141A
small nuclear RNA U2 at 38AB b
U2 snRNA, U2, dU2, U2:38ABb, U2-141B
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, 70K, U170K
small ribonucleoprotein particle U1 subunit C
snRNP-U1, snRNPC, U1C
Small nuclear ribonucleoprotein G
SmG, snRNPG
Spliceosomal protein on the X
squid
hrp40, l(3)j4B4, RRM3, l(3)EP3631, hnRNP A
U2A
U2A', l(2)43Ee, dU2A'
U2 small nuclear riboprotein auxiliary factor 38
U2AF, dU2AF38, dU2AF38
U2 small nuclear riboprotein auxiliary factor 50
dU2AF50, U2AF, l(1)9-21, dU2AF50, l(1)14Cc
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-A
SPLICEOSOME COMPLEX A
Intron definition complex
Pre-spliceosome
Complex A
Secondary FlyBase ID(s)
References (4)