FB2025_01 , released February 20, 2025
Complex: SPLICEOSOME COMPLEX A
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General Information
Name
SPLICEOSOME COMPLEX A
Species
D. melanogaster
Symbol
SPL-C-A
FlyBase ID
FBgg0000535
Date last reviewed
2016-09-05
Number of members
50
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Source Material
The SPLICEOSOME COMPLEX A Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
U2-type prespliceosome
Related Gene Groups
Parent group(s)
SPLICEOSOME COMPLEX INTERMEDIATES
Members (50)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG4119
BcDNA:LD23634
(Cvitkovic and Jurica, 2013)
CG4887
(Cvitkovic and Jurica, 2013)
CG4896
(Cvitkovic and Jurica, 2013)
CG9346
(Cvitkovic and Jurica, 2013)
CG31550
(Cvitkovic and Jurica, 2013)
Dhx15
DEAH-box helicase 15
(Cvitkovic and Jurica, 2013)
hfp
half pint
pUf68, pUbsf, DPUF68, PUF60, poly U binding factor 68kD
(Cvitkovic and Jurica, 2013)
Hrb87F
Heterogeneous nuclear ribonucleoprotein at 87F
hrp36, P11, hnRNPA1, Hrb87Fa, Q16
(Cvitkovic and Jurica, 2013)
Hrb98DE
Heterogeneous nuclear ribonucleoprotein at 98DE
hrp38
(Cvitkovic and Jurica, 2013)
noi
noisette
SF3A3, l(3)j3E7
(Cvitkovic and Jurica, 2013)
Phf5a
PHD finger protein 5a
(Cvitkovic and Jurica, 2013)
Prp5
pre-mRNA processing factor 5
(Cvitkovic and Jurica, 2013)
Prp40
pre-mRNA processing factor 40
(Cvitkovic and Jurica, 2013)
scaf6
SR-related CTD associated factor 6
BP1047, BP1040
(Cvitkovic and Jurica, 2013)
SF1
Splicing factor 1
(Cvitkovic and Jurica, 2013)
Sf3a1
Splicing factor 3a subunit 1
(Cvitkovic and Jurica, 2013)
Sf3a2
Splicing factor 3a subunit 2
(Cvitkovic and Jurica, 2013)
Sf3b1
Splicing factor 3b subunit 1
(Cvitkovic and Jurica, 2013)
Sf3b2
Splicing factor 3b subunit 2
(Cvitkovic and Jurica, 2013)
Sf3b3
Splicing factor 3b subunit 3
(Cvitkovic and Jurica, 2013)
Sf3b5
Splicing factor 3b subunit 5
(Cvitkovic and Jurica, 2013)
Sf3b6
Splicing factor 3b subunit 6
(Cvitkovic and Jurica, 2013)
SmB
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
(Cvitkovic and Jurica, 2013)
SmD1
Small ribonucleoprotein particle protein SmD1
snRNP69D
(Cvitkovic and Jurica, 2013)
SmD2
Small ribonucleoprotein particle protein SmD2
snRNP2
(Cvitkovic and Jurica, 2013)
SmD3
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
(Cvitkovic and Jurica, 2013)
SmE
Small ribonucleoprotein particle protein SmE
snRNPE
(Cvitkovic and Jurica, 2013)
SmF
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
(Cvitkovic and Jurica, 2013)
snf
sans fille
fs(1)1621, fs(1)A1621, liz, SNF/D25, splicing necessary factor
(Cvitkovic and Jurica, 2013)
snRNA:U1:21D
small nuclear RNA U1 at 21D
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:21D
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U1:82Eb
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1:82Eb, U1-82.3, U1snRNA
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U1:95Ca
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, snRNA:U1
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U1:95Cb
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1:95Cb, U1snRNA, snRNA:U1
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U1:95Cc
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cc
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U2:14B
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, U2:14B, U2-14B
(Lu and Matera, 2014)
snRNA:U2:34ABa
small nuclear RNA U2 at 34AB a
U2, U2 snRNA, dU2, U2-131A, U2:34ABa
(Lu and Matera, 2014)
snRNA:U2:34ABb
small nuclear RNA U2 at 34AB b
U2, U2 snRNA, dU2, U2-131B, U2:34ABb
(Lu and Matera, 2014)
snRNA:U2:34ABc
small nuclear RNA U2 at 34AB c
U2, U2 snRNA, dU2, snRNA:U2
(Lu and Matera, 2014)
snRNA:U2:38ABa
small nuclear RNA U2 at 38AB a
U2, U2 snRNA, dU2, U2-141A, U2:38ABa
(Cvitkovic and Jurica, 2013)
snRNA:U2:38ABb
small nuclear RNA U2 at 38AB b
U2, U2 snRNA, dU2, U2:38ABb, U2-141B
(Lu and Matera, 2014)
snRNP-U1-70K
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, 70K, Dm70K
(Cvitkovic and Jurica, 2013)
snRNP-U1-C
small ribonucleoprotein particle U1 subunit C
snRNP-U1, U1C, snRNPC
(Cvitkovic and Jurica, 2013)
SNRPG
Small nuclear ribonucleoprotein G
SmG, snRNPG
(Cvitkovic and Jurica, 2013)
Spf30
Splicing factor 30
(Cvitkovic and Jurica, 2013)
Spf45
Spf45
dSPF45
(Cvitkovic and Jurica, 2013)
Spx
Spliceosomal protein on the X
(Cvitkovic and Jurica, 2013)
sqd
squid
hrp40, l(3)j4B4, hnRNP A, l(3)EP3631, RRM3
(Cvitkovic and Jurica, 2013)
U2A
U2A
U2A', l(2)43Ee, dU2A'
(Cvitkovic and Jurica, 2013)
U2af38
U2 small nuclear riboprotein auxiliary factor 38
U2AF, dU2AF38, dU2AF38
(Cvitkovic and Jurica, 2013)
U2af50
U2 small nuclear riboprotein auxiliary factor 50
dU2AF50, U2AF, l(1)9-21, dU2AF50, l(1)14Cc
(Cvitkovic and Jurica, 2013)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-A
SPLICEOSOME COMPLEX A
Intron definition complex
Pre-spliceosome
Complex A
Secondary FlyBase ID(s)
References (4)