Open Close
General Information
Name
SPLICEOSOME COMPLEX A
Species
D. melanogaster
Symbol
SPL-C-A
FlyBase ID
FBgg0000535
Date last reviewed
2016-09-05
Number of members
50
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Source Material
The SPLICEOSOME COMPLEX A Gene Group has been compiled by FlyBase curators using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988.
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (50)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
DEAH-box helicase 15
half pint
pUf68, pUbsf, DPUF68, poly U binding factor 68kD, PUF60
Heterogeneous nuclear ribonucleoprotein at 87F
hrp36, P11, hnRNPA1, hnRNPA2, Hrb87Fa
Heterogeneous nuclear ribonucleoprotein at 98DE
hrp38
noisette
SF3A3, l(3)j3E7
PHD finger protein 5a
SR-related CTD associated factor 6
BP1040, BP1047
Splicing factor 3a subunit 1
Splicing factor 3a subunit 2
Splicing factor 3b subunit 1
Splicing factor 3b subunit 2
Splicing factor 3b subunit 3
Splicing factor 3b subunit 5
Splicing factor 3b subunit 6
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmD1
snRNP69D
Small ribonucleoprotein particle protein SmD2
snRNP2
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
Small ribonucleoprotein particle protein SmE
snRNPE
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
sans fille
fs(1)1621, fs(1)A1621, liz, SNF/D25, splicing necessary factor
small nuclear RNA U1 at 21D
U1, U1 snRNA, U1snRNA, snRNA:U1, U1 small nuclear RNA
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1snRNA, U1-82.3, U1:82Eb
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, U1-95.1
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cb
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cc
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, U2:14B, U2-14B
small nuclear RNA U2 at 34AB a
U2 snRNA, U2, dU2, U2:34ABa, U2-131A
small nuclear RNA U2 at 34AB b
U2 snRNA, U2, dU2, U2:34ABb, U2-131B
small nuclear RNA U2 at 34AB c
U2 snRNA, U2, dU2, snRNA:U2
small nuclear RNA U2 at 38AB a
U2 snRNA, U2, dU2, U2:38ABa, snRNA:U2
small nuclear RNA U2 at 38AB b
U2 snRNA, U2, dU2, U2:38ABb, U2-141B
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, snRNP27D, 70K
small ribonucleoprotein particle U1 subunit C
snRNP-U1, U1C, snRNPC
Small nuclear ribonucleoprotein G
SmG, snRNPG
Spliceosomal protein on the X
squid
hrp40, l(3)j4B4, l(3)EP3631, RRM3, hnRNP A
U2A
U2A', l(2)43Ee, dU2A'
U2 small nuclear riboprotein auxiliary factor 38
U2AF, dU2AF38, dU2AF38
U2 small nuclear riboprotein auxiliary factor 50
dU2AF50, U2AF, l(1)9-21, dU2AF50, l(1)14Cc
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-A
SPLICEOSOME COMPLEX A
Intron definition complex
Pre-spliceosome
Complex A
Secondary FlyBase ID(s)
References (4)