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General Information
Name
SPLICEOSOME COMPLEX C
Species
D. melanogaster
Symbol
SPL-C-C
FlyBase ID
FBgg0000536
Date last reviewed
2016-09-05
Number of members
91
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex B undergoes a number of structural rearrangements and U4 and U1 snRNPs dissociate to generate complex C, the catalytic spliceosome. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Complex B goes through transition intermediates Bact and B* prior to forming complex C (PMID:24452469 and PMID:23118483). These have not been curated as gene groups.
Source Material
The SPLICEOSOME COMPLEX C Gene Group has been compiled by FlyBase curators using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988.
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (91)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Bicoid interacting protein 1
dSAP18, SAP18
Cdc2-related kinase
Dcdrk
Cell division cycle 5
cdc5-like
eIF4AIII, l(3)84Fi, eIF4A3
crooked neck
yok, l(1)2, EG:30B8.1, l30, yolky
Heat shock protein cognate 1
Hsc70, Hsc1
lethal (1) 10Bb
l(1)G0169
lethal (2) 37Cb
l(2)E104, Cb
mago nashi
mgn, l(2)57Ca
noisette
SF3A3, l(3)j3E7
PHD finger protein 5a
pre-mRNA processing factor 8
Pre-RNA processing factor 19
l(2)07838, Gbp
Splicing factor 3a subunit 1
Splicing factor 3a subunit 2
Splicing factor 3b subunit 1
Splicing factor 3b subunit 2
Splicing factor 3b subunit 3
Splicing factor 3b subunit 5
Splicing factor 3b subunit 6
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmD1
snRNP69D
Small ribonucleoprotein particle protein SmD2
snRNP2
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
Small ribonucleoprotein particle protein SmE
snRNPE
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, U2:14B, U2-14B
small nuclear RNA U2 at 34AB a
U2 snRNA, U2, dU2, U2:34ABa, U2-131A
small nuclear RNA U2 at 34AB b
U2 snRNA, U2, dU2, U2:34ABb, U2-131B
small nuclear RNA U2 at 34AB c
U2 snRNA, U2, dU2, snRNA:U2
small nuclear RNA U2 at 38AB a
U2 snRNA, U2, dU2, U2:38ABa, snRNA:U2
small nuclear RNA U2 at 38AB b
U2 snRNA, U2, dU2, U2:38ABb, U2-141B
small nuclear RNA U5 at 14B
U5, U5 snRNA, dU5, U5:14B, snRNA:U5
small nuclear RNA U5 at 23D
U5, U5 snRNA, U5:23D, dU5, snRNA:U5
small nuclear RNA U5 at 34A
U5, U5 snRNA, U5:34A, dU5, snRNA:U5
small nuclear RNA U5 at 35D
U5, U5 snRNA, dU5, U5:35D
small nuclear RNA U5 at 38AB a
U5, U5 snRNA, dU5, snRNA:U5, U5:38ABa
small nuclear RNA U5 at 38AB b
U5, U5 snRNA, dU5, snRNA:U5, U5:38ABb
small nuclear RNA U5 at 63BC
U5, U5:63BC, U5 snRNA, dU5, snRNA:U5
small nuclear RNA U6 at 96A a
U6, U6-1, U6 snRNA, U6 RNA, snRNA-b
small nuclear RNA U6 at 96A b
U6, U6-2, U6:96Ab, U6 RNA, U6 snRNA
small nuclear RNA U6 at 96A c
U6, U6 snRNA, U6 RNA, U6-3, snRNA-b
Small nuclear ribonucleoprotein G
SmG, snRNPG
Spliceosomal protein on the X
Transport and Golgi organization 4
tsunagi
Y14, Y14/Tsunagi
U2A
U2A', l(2)43Ee, dU2A'
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPLICEOSOME COMPLEX C
SPL-C-C
SLP-C-C
Secondary FlyBase ID(s)
References (4)