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General Information
Name
SPLICEOSOME COMPLEX B
Species
D. melanogaster
Symbol
SPL-C-B
FlyBase ID
FBgg0000539
Date last reviewed
2016-09-05
Number of members
91
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. After the assembly of complex A on pre-mRNA, the U4-U6 and U5 snRNPs are recruited as a preassembled tri-snRNP to form complex B. U5 snRNP binds exons at the 5' site. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Source Material
The SPLICEOSOME COMPLEX B Gene Group has been compiled by FlyBase curators using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988.
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (91)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cell division cycle 5
cdc5-like
crooked neck
yok, l(1)2, EG:30B8.1, l30, yolky
DEAH-box helicase 15
lethal (1) 10Bb
l(1)G0169
Microfibril-associated protein 1
noisette
SF3A3, l(3)j3E7
PHD finger protein 5a
Precursor RNA processing 3
pre-mRNA processing factor 8
Pre-RNA processing factor 19
l(2)07838, Gbp
Pre-mRNA processing factor 31
pre-mRNA processing factor 38
Splicing factor 3a subunit 1
Splicing factor 3a subunit 2
Splicing factor 3b subunit 1
Splicing factor 3b subunit 2
Splicing factor 3b subunit 3
Splicing factor 3b subunit 5
Splicing factor 3b subunit 6
septin interacting protein 1
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmD1
snRNP69D
Small ribonucleoprotein particle protein SmD2
snRNP2
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
Small ribonucleoprotein particle protein SmE
snRNPE
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
Smu1 spliceosomal factor
sans fille
fs(1)1621, fs(1)A1621, liz, SNF/D25, splicing necessary factor
small nuclear RNA U1 at 21D
U1, U1 snRNA, U1snRNA, snRNA:U1, U1 small nuclear RNA
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1snRNA, U1-82.3, U1:82Eb
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, U1-95.1
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cb
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cc
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, U2:14B, U2-14B
small nuclear RNA U2 at 34AB a
U2 snRNA, U2, dU2, U2:34ABa, U2-131A
small nuclear RNA U2 at 34AB b
U2 snRNA, U2, dU2, U2:34ABb, U2-131B
small nuclear RNA U2 at 34AB c
U2 snRNA, U2, dU2, snRNA:U2
small nuclear RNA U2 at 38AB a
U2 snRNA, U2, dU2, U2:38ABa, snRNA:U2
small nuclear RNA U2 at 38AB b
U2 snRNA, U2, dU2, U2:38ABb, U2-141B
small nuclear RNA U4 at 25F
U4, U4 snRNA, dU4, snRNA, U425F, U4-25F
small nuclear RNA U4 at 38AB
U4, U4 snRNA, U4-1, U4:38AB, dU4
small nuclear RNA U4 at 39B
U4, U4 snRNA, U4-2, U4:39B, U4-39B
small nuclear RNA U5 at 14B
U5, U5 snRNA, dU5, U5:14B, snRNA:U5
small nuclear RNA U5 at 23D
U5, U5 snRNA, U5:23D, dU5, snRNA:U5
small nuclear RNA U5 at 34A
U5, U5 snRNA, U5:34A, dU5, snRNA:U5
small nuclear RNA U5 at 35D
U5, U5 snRNA, dU5, U5:35D
small nuclear RNA U5 at 38AB a
U5, U5 snRNA, dU5, snRNA:U5, U5:38ABa
small nuclear RNA U5 at 38AB b
U5, U5 snRNA, dU5, snRNA:U5, U5:38ABb
small nuclear RNA U5 at 63BC
U5, U5:63BC, U5 snRNA, dU5, snRNA:U5
small nuclear RNA U6 at 96A a
U6, U6-1, U6 snRNA, U6 RNA, snRNA-b
small nuclear RNA U6 at 96A b
U6, U6-2, U6:96Ab, U6 RNA, U6 snRNA
small nuclear RNA U6 at 96A c
U6, U6 snRNA, U6 RNA, U6-3, snRNA-b
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, snRNP27D, 70K
small ribonucleoprotein particle U1 subunit C
snRNP-U1, U1C, snRNPC
Small nuclear ribonucleoprotein G
SmG, snRNPG
Spliceosomal protein on the X
Transport and Golgi organization 4
U2A
U2A', l(2)43Ee, dU2A'
U4-U6 small nuclear riboprotein factor 60K
Ubiquitin specific protease 39
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-B
SPLICEOSOME COMPLEX B
Complex B
Fully assembled spiceosome
Secondary FlyBase ID(s)
References (4)