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General Information
Name
SPLICEOSOME COMPLEX B
Species
D. melanogaster
Symbol
SPL-C-B
FlyBase ID
FBgg0000539
Date last reviewed
2016-09-05
Number of members
91
Description
Description

Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. After the assembly of complex A on pre-mRNA, the U4-U6 and U5 snRNPs are recruited as a preassembled tri-snRNP to form complex B. U5 snRNP binds exons at the 5' site. (Adapted from PMID:24452469 and PMID:23118483).

Notes on Group
Source Material
The SPLICEOSOME COMPLEX B Gene Group has been compiled by FlyBase curators using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (91)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cell division cycle 5
cdc5-like
crooked neck
yok, EG:30B8.1, l(1)2, yolky, l30
DEAH-box helicase 15
lethal (1) 10Bb
l(1)G0169
Microfibril-associated protein 1
noisette
SF3A3, l(3)j3E7
PHD finger protein 5a
Precursor RNA processing 3
pre-mRNA processing factor 8
Pre-RNA processing factor 19
l(2)07838, Gbp
Pre-mRNA processing factor 31
pre-mRNA processing factor 38
Splicing factor 3a subunit 1
Splicing factor 3a subunit 2
Splicing factor 3b subunit 1
Splicing factor 3b subunit 2
Splicing factor 3b subunit 3
Splicing factor 3b subunit 5
Splicing factor 3b subunit 6
septin interacting protein 1
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmD1
snRNP69D
Small ribonucleoprotein particle protein SmD2
snRNP2
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
Small ribonucleoprotein particle protein SmE
snRNPE
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
Smu1 spliceosomal factor
sans fille
fs(1)1621, fs(1)A1621, liz, splicing necessary factor, SNF/D25
small nuclear RNA U1 at 21D
U1, U1 snRNA, snRNA:U1, U1snRNA, U1-21.1
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1:82Eb, U1-82.3, U1snRNA
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, U1snRNA
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1snRNA, U1:95Cb, snRNA:U1
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1-95.3
small nuclear RNA U2 at 14B
U2 snRNA, U2, dU2, U2-14B, snRNA:U2
small nuclear RNA U2 at 34AB a
U2 snRNA, U2, dU2, snRNA:U2, U2:34ABa
small nuclear RNA U2 at 34AB b
U2 snRNA, U2, dU2, U2:34ABb, U2-131B
small nuclear RNA U2 at 34AB c
U2 snRNA, U2, dU2, snRNA:U2
small nuclear RNA U2 at 38AB a
U2 snRNA, U2, dU2, U2-141A, snRNA:U2
small nuclear RNA U2 at 38AB b
U2 snRNA, U2, dU2, U2-141B, U2:38ABb
small nuclear RNA U4 at 25F
U4, U4 snRNA, snRNA, U425F, dU4, U4-25F
small nuclear RNA U4 at 38AB
U4, U4 snRNA, U4-1, U4:38AB, snRNA:U4
small nuclear RNA U4 at 39B
U4, U4 snRNA, U4-2, U4:39B, l(2)k09410
small nuclear RNA U5 at 14B
U5, U5 snRNA, U5:14B, dU5, snRNA:U5
small nuclear RNA U5 at 23D
U5, U5:23D, U5 snRNA, dU5, snRNA:U5
small nuclear RNA U5 at 34A
U5, U5:34A, U5 snRNA, dU5, snRNA:U5
small nuclear RNA U5 at 35D
U5, U5 snRNA, U5:35D, dU5
small nuclear RNA U5 at 38AB a
U5, U5 snRNA, U5:38ABa, snRNA:U5, dU5
small nuclear RNA U5 at 38AB b
U5, U5 snRNA, dU5, snRNA:U5, U5:38ABb
small nuclear RNA U5 at 63BC
U5, U5:63BC, U5 snRNA, snRNA:U5, dU5
small nuclear RNA U6 at 96A a
U6, U6 snRNA, U6-1, snRNA-b, U6 RNA
small nuclear RNA U6 at 96A b
U6, U6-2, U6:96Ab, U6 snRNA, U6 RNA
small nuclear RNA U6 at 96A c
U6, U6 snRNA, U6snRNA, U6-3, snRNA:U6
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, dU1-70K, Dm70K
small ribonucleoprotein particle U1 subunit C
snRNP-U1, snRNPC, U1C
Small nuclear ribonucleoprotein G
SmG, snRNPG
Spliceosomal protein on the X
Transport and Golgi organization 4
U2A
U2A', l(2)43Ee, dU2A'
U4-U6 small nuclear riboprotein factor 60K
Ubiquitin specific protease 39
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-B
SPLICEOSOME COMPLEX B
Complex B
Fully assembled spiceosome
Secondary FlyBase ID(s)
References (4)