FB2025_02 , released April 17, 2025
Complex: SPLICEOSOME COMPLEX B
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General Information
Name
SPLICEOSOME COMPLEX B
Species
D. melanogaster
Symbol
SPL-C-B
FlyBase ID
FBgg0000539
Date last reviewed
2016-09-05
Number of members
91
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. After the assembly of complex A on pre-mRNA, the U4-U6 and U5 snRNPs are recruited as a preassembled tri-snRNP to form complex B. U5 snRNP binds exons at the 5' site. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Source Material
The SPLICEOSOME COMPLEX B Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
U2-type precatalytic spliceosome
Related Gene Groups
Parent group(s)
SPLICEOSOME COMPLEX INTERMEDIATES
Members (91)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-B
SPLICEOSOME COMPLEX B
Complex B
Fully assembled spiceosome
Secondary FlyBase ID(s)
References (4)