FB2025_01 , released February 20, 2025
Complex: SPLICEOSOME COMPLEX B
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General Information
Name
SPLICEOSOME COMPLEX B
Species
D. melanogaster
Symbol
SPL-C-B
FlyBase ID
FBgg0000539
Date last reviewed
2016-09-05
Number of members
91
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. After the assembly of complex A on pre-mRNA, the U4-U6 and U5 snRNPs are recruited as a preassembled tri-snRNP to form complex B. U5 snRNP binds exons at the 5' site. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Source Material
The SPLICEOSOME COMPLEX B Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
U2-type precatalytic spliceosome
Related Gene Groups
Parent group(s)
SPLICEOSOME COMPLEX INTERMEDIATES
Members (91)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
BCAS2
BCAS2
dBCAS2
(Cvitkovic and Jurica, 2013)
beag
beag
(Cvitkovic and Jurica, 2013)
Brr2
Brr2 U5 snRNP complex subunit
l(3)72Ab
(Cvitkovic and Jurica, 2013)
Bx42
Bx42
Skip
(Cvitkovic and Jurica, 2013)
c12.1
c12.1
(Cvitkovic and Jurica, 2013)
Cdc5
Cell division cycle 5
cdc5-like
(Cvitkovic and Jurica, 2013)
CG2021
l(3)neo7, l(3)62Be
(Cvitkovic and Jurica, 2013)
CG2685
EG:100G10.1
(Cvitkovic and Jurica, 2013)
CG3436
(Cvitkovic and Jurica, 2013)
CG4291
(Cvitkovic and Jurica, 2013)
CG4849
eEF2
(Cvitkovic and Jurica, 2013)
CG5808
BcDNA:GH01073
(Cvitkovic and Jurica, 2013)
CG6610
(Cvitkovic and Jurica, 2013)
CG6686
(Cvitkovic and Jurica, 2013)
CG9344
(Cvitkovic and Jurica, 2013)
CG9667
(Cvitkovic and Jurica, 2013)
CG10333
DmPrp28, DmRH19
(Cvitkovic and Jurica, 2013)
CG10418
(Cvitkovic and Jurica, 2013)
CG11586
(Cvitkovic and Jurica, 2013)
CG11964
(Cvitkovic and Jurica, 2013)
CG14641
(Cvitkovic and Jurica, 2013)
CG17266
(Cvitkovic and Jurica, 2013)
CG17768
(Cvitkovic and Jurica, 2013)
crn
crooked neck
yok, EG:30B8.1, l(1)2, yolky, l30
(Cvitkovic and Jurica, 2013)
cyp33
cyclophilin-33
(Cvitkovic and Jurica, 2013)
Cypl
Cyclophilin-like
(Cvitkovic and Jurica, 2013)
Dhx15
DEAH-box helicase 15
(Cvitkovic and Jurica, 2013)
Dim1
Dim1
(Cvitkovic and Jurica, 2013)
fand
fandango
fas, XAB2
(Cvitkovic and Jurica, 2013)
hoip
hoi-polloi
l(2)FE3
(Cvitkovic and Jurica, 2013)
l(1)10Bb
lethal (1) 10Bb
l(1)G0169
(Cvitkovic and Jurica, 2013)
LSm3
Like Sm 3
(Cvitkovic and Jurica, 2013)
LSm7
Like Sm 7
(Cvitkovic and Jurica, 2013)
Mfap1
Microfibril-associated protein 1
(Cvitkovic and Jurica, 2013)
noi
noisette
SF3A3, l(3)j3E7
(Cvitkovic and Jurica, 2013)
Phf5a
PHD finger protein 5a
(Cvitkovic and Jurica, 2013)
Prp3
Precursor RNA processing 3
(Cvitkovic and Jurica, 2013)
Prp6
pre-mRNA processing factor 6
(Cvitkovic and Jurica, 2013)
Prp8
pre-mRNA processing factor 8
(Cvitkovic and Jurica, 2013)
Prp19
Pre-RNA processing factor 19
l(2)07838, Gbp
(Cvitkovic and Jurica, 2013)
Prp31
Pre-mRNA processing factor 31
(Cvitkovic and Jurica, 2013)
Prp38
pre-mRNA processing factor 38
(Cvitkovic and Jurica, 2013)
salsa
salsa
(Cvitkovic and Jurica, 2013)
Sf3a1
Splicing factor 3a subunit 1
(Cvitkovic and Jurica, 2013)
Sf3a2
Splicing factor 3a subunit 2
(Cvitkovic and Jurica, 2013)
Sf3b1
Splicing factor 3b subunit 1
(Cvitkovic and Jurica, 2013)
Sf3b2
Splicing factor 3b subunit 2
(Cvitkovic and Jurica, 2013)
Sf3b3
Splicing factor 3b subunit 3
(Cvitkovic and Jurica, 2013)
Sf3b5
Splicing factor 3b subunit 5
(Cvitkovic and Jurica, 2013)
Sf3b6
Splicing factor 3b subunit 6
(Cvitkovic and Jurica, 2013)
sip1
septin interacting protein 1
(Cvitkovic and Jurica, 2013)
SmB
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
(Cvitkovic and Jurica, 2013)
SmD1
Small ribonucleoprotein particle protein SmD1
snRNP69D
(Cvitkovic and Jurica, 2013)
SmD2
Small ribonucleoprotein particle protein SmD2
snRNP2
(Cvitkovic and Jurica, 2013)
SmD3
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
(Cvitkovic and Jurica, 2013)
SmE
Small ribonucleoprotein particle protein SmE
snRNPE
(Cvitkovic and Jurica, 2013)
SmF
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
(Cvitkovic and Jurica, 2013)
Smu1
Smu1 spliceosomal factor
(Cvitkovic and Jurica, 2013)
snf
sans fille
fs(1)1621, fs(1)A1621, liz, SNF/D25, splicing necessary factor
(Cvitkovic and Jurica, 2013)
snRNA:U1:21D
small nuclear RNA U1 at 21D
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:21D
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U1:82Eb
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1:82Eb, U1-82.3, U1snRNA
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U1:95Ca
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, snRNA:U1
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U1:95Cb
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1:95Cb, U1snRNA, snRNA:U1
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U1:95Cc
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cc
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U2:14B
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, U2:14B, U2-14B
(Lu and Matera, 2014)
snRNA:U2:34ABa
small nuclear RNA U2 at 34AB a
U2, U2 snRNA, dU2, U2-131A, U2:34ABa
(Lu and Matera, 2014)
snRNA:U2:34ABb
small nuclear RNA U2 at 34AB b
U2, U2 snRNA, dU2, U2-131B, U2:34ABb
(Lu and Matera, 2014)
snRNA:U2:34ABc
small nuclear RNA U2 at 34AB c
U2, U2 snRNA, dU2, snRNA:U2
(Lu and Matera, 2014)
snRNA:U2:38ABa
small nuclear RNA U2 at 38AB a
U2, U2 snRNA, dU2, U2-141A, U2:38ABa
(Cvitkovic and Jurica, 2013)
snRNA:U2:38ABb
small nuclear RNA U2 at 38AB b
U2, U2 snRNA, dU2, U2:38ABb, U2-141B
(Lu and Matera, 2014)
snRNA:U4:25F
small nuclear RNA U4 at 25F
U4, U4 snRNA, U4-25F, snRNA, U425F, dU4
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013)
snRNA:U4:38AB
small nuclear RNA U4 at 38AB
U4, U4 snRNA, U4-1, U4:38AB, snRNA:U4
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U4:39B
small nuclear RNA U4 at 39B
U4, U4 snRNA, U4-2, U4:39B, U4-39B
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:14B
small nuclear RNA U5 at 14B
U5, U5 snRNA, U5:14B, snRNA:U5, dU5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:23D
small nuclear RNA U5 at 23D
U5, U5:23D, U5 snRNA, dU5, snRNA:U5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:34A
small nuclear RNA U5 at 34A
U5, U5 snRNA, U5:34A, dU5, snRNA:U5
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U5:35D
small nuclear RNA U5 at 35D
U5, U5 snRNA, dU5, U5:35D
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:38ABa
small nuclear RNA U5 at 38AB a
U5, U5 snRNA, U5:38ABa, dU5, snRNA:U5
(Lu and Matera, 2014)
snRNA:U5:38ABb
small nuclear RNA U5 at 38AB b
U5, U5 snRNA, snRNA:U5, dU5, U5:38ABb
(Lu and Matera, 2014)
snRNA:U5:63BC
small nuclear RNA U5 at 63BC
U5, U5:63BC, U5 snRNA, dU5, snRNA:U5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U6:96Aa
small nuclear RNA U6 at 96A a
U6, U6-1, U6 snRNA, snRNA:U6, snRNA-b
(Saluz et al., 1988)
snRNA:U6:96Ab
small nuclear RNA U6 at 96A b
U6, U6-2, U6:96Ab, U6 RNA, U6 snRNA
(Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U6:96Ac
small nuclear RNA U6 at 96A c
U6, U6 snRNA, U6-3, snRNA:U6, U6:96Ac
(Saluz et al., 1988)
snRNP-U1-70K
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, 70K, Dm70K
(Cvitkovic and Jurica, 2013)
snRNP-U1-C
small ribonucleoprotein particle U1 subunit C
snRNP-U1, U1C, snRNPC
(Cvitkovic and Jurica, 2013)
SNRPG
Small nuclear ribonucleoprotein G
SmG, snRNPG
(Cvitkovic and Jurica, 2013)
Spx
Spliceosomal protein on the X
(Cvitkovic and Jurica, 2013)
Tango4
Transport and Golgi organization 4
(Cvitkovic and Jurica, 2013)
U2A
U2A
U2A', l(2)43Ee, dU2A'
(Cvitkovic and Jurica, 2013)
U4-U6-60K
U4-U6 small nuclear riboprotein factor 60K
(Cvitkovic and Jurica, 2013)
Usp39
Ubiquitin specific protease 39
(Cvitkovic and Jurica, 2013)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-B
SPLICEOSOME COMPLEX B
Complex B
Fully assembled spiceosome
Secondary FlyBase ID(s)
References (4)