General Information
Name
ATP-BINDING CASSETTE TRANSPORTERS
Species
D. melanogaster
Symbol
ABC-T
FlyBase ID
FBgg0000547
Date last reviewed
2016-09-06
Number of members
52
Description
Description
The ATP-binding cassette (ABC) transporter family are primary active transporters that use ATP hydrolysis to drive the transport of substrates across the membrane. A functional transporter contains 12 transmembrane domains and 2 cytoplasmic nucleotide binding domains. The transporter may be encoded by one polypeptide (full transporters) or formed by a dimer of half transporters. (Adapted from FBrf0224053).
Notes on Group
Source Material
The ATP-BINDING CASSETTE TRANSPORTERS Gene Group has been compiled by FlyBase curators using the following publication(s): Paulsen et al., 2013, Dermauw and Van Leeuwen, 2014, and Dean et al., 2001.
Key Gene Ontology (GO) terms
Biological Process
Related Gene Groups
Members (52)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
ABC-T
ATP-BINDING CASSETTE TRANSPORTERS
ABC transporters
ABC gene family
Secondary FlyBase ID(s)
References (4)
FlyBase analysis
FlyBase, 2014-, FlyBase Gene Group information.
FlyBase Gene Group information. [FBrf0225556]
Review
Dermauw and Van Leeuwen, 2014, Insect Biochem. Mol. Biol. 45C: 89--110
The ABC gene family in arthropods: Comparative genomics and role in insecticide transport and resistance. [FBrf0224053]
Dean et al., 2001, Genome Res. 11: 1156--1166
The human ATP-binding cassette (ABC) transporter superfamily. [FBrf0159553]
Website
Paulsen et al., 2013, TransportDB.
TransportDB. [FBrf0233553]