FB2025_01 , released February 20, 2025
Gene Group: NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE
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General Information
Name
NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE
Species
D. melanogaster
Symbol
GLURII
FlyBase ID
FBgg0000570
Date last reviewed
2024-02-29
Number of members
5
Description
Description
In Drosophila, neuromuscular junction type A and type B glutamate receptors are heterotetramers assembled from either GluRIIA or GluRIIB plus other GluRII subunits. In response to the neurotransmitter, glutamate, they conduct Ca2+. (Adapted from FBrf0228432).
Notes on Group

Drosophila NMJ ionotropic glutamate receptors have a pharmacological profile distinct from vertebrate non-NMDA glutamate receptors in that they can be activated by the agonist quisqualate, but do not respond to AMPA or kainate (FBrf0228432).

Source Material
The NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE Gene Group has been compiled using the following publication(s): Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, and Lee et al., 2009 .
Key Gene Ontology (GO) terms
Molecular Function
glutamate-gated calcium ion channel activity
Biological Process
calcium ion transmembrane transport
Cellular Component
neuromuscular junction
ionotropic glutamate receptor complex
Related Gene Groups
Parent group(s)
CALCIUM CHANNEL SUBUNITS
IONOTROPIC GLUTAMATE RECEPTORS
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
GluRIIA
Glutamate receptor IIA
DGluRIIA, DGluR-II, DGluR-IIA, GluR, Glu-RIIA
(Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, Lee et al., 2009)
GluRIIB
Glutamate receptor IIB
DGluRIIB
(Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, Lee et al., 2009)
GluRIIC
Glutamate receptor IIC
GluRIII, DGluRIII, DGluRIIC, GluRII-C, GluR
(Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, Lee et al., 2009)
GluRIID
Glutamate receptor IID
KaiRIA, brec
(Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, Lee et al., 2009)
GluRIIE
Glutamate receptor IIE
(Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, Lee et al., 2009)
External Data
Equivalent Group(s)
Other resource(s)

[Transporter Classification Database:The Glutamate-gated Ion Channel (GIC) Family of Neurotransmitter Receptors](https://tcdb.org/search/result.php?tc=1.A.10)

Synonyms and Secondary IDs
Synonym(s)
GLURII
NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE
Neuromuscular junction ionotropic glutamate receptors
NMJ ionotropic glutamate receptors
NMJ iGluRs
Secondary FlyBase ID(s)
References (8)