FB2017_02, released April 18, 2017

Gene Group: PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS GENES

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General Information
Name
PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS GENES
Species
D. melanogaster
Symbol
PIG
FlyBase ID
FBgg0000617
Date last reviewed
2017-02-07
Number of members
26
Description
Description
Phosphatidylinositol glycan anchor biosynthesis (PIG) genes, characterized extensively in humans, are involved in the synthesis of glycosylphosphatidylinositols (GPI) and their transfer to proteins to act as a lipid bilayer anchor. GPI is synthesized in the endoplasmic reticulum and is attached to the carboxyl terminus of a protein that has a GPI-attachment signal sequence. (Adapted from FBrf0220328, PMID:11102867 and PMID:19883648).
Notes on Group
Source Material
The PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS GENES Gene Group has been compiled by FlyBase curators using the following publication(s): Satoh et al., 2013.
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
GPI anchor biosynthetic process
Cellular Component
integral component of endoplasmic reticulum membrane
Related Gene Groups
Other related group(s)
PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS COMPLEXES
Members (26)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
GAA1
Glycosylphosphatidylinositol anchor attachment 1
(Satoh et al., 2013)
PGAP1
Post-GPI attachment to proteins 1
(Satoh et al., 2013)
PGAP2
Post-GPI attachment to proteins 2
(Satoh et al., 2013)
PGAP3
Post-GPI attachment to proteins 3
(Satoh et al., 2013)
PGAP5
Post-GPI attachment to proteins 5
(Satoh et al., 2013)
PIG-A
Phosphatidylinositol glycan anchor biosynthesis class A
(Satoh et al., 2013)
PIG-B
Phosphatidylinositol glycan anchor biosynthesis class B
(Satoh et al., 2013)
PIG-C
Phosphatidylinositol glycan anchor biosynthesis class C
(Satoh et al., 2013)
PIG-F
Phosphatidylinositol glycan anchor biosynthesis class F
(Satoh et al., 2013)
PIG-G
Phosphatidylinositol glycan anchor biosynthesis class G
(Satoh et al., 2013)
PIG-H
Phosphatidylinositol glycan anchor biosynthesis class H
(Satoh et al., 2013)
PIG-K
Phosphatidylinositol glycan anchor biosynthesis class K
EG:133E12.3
(Satoh et al., 2013)
PIG-L
Phosphatidylinositol glycan anchor biosynthesis class L
(Satoh et al., 2013)
PIG-M
Phosphatidylinositol glycan anchor biosynthesis class M
(Satoh et al., 2013)
PIG-N
Phosphatidylinositol glycan anchor biosynthesis class N
(Satoh et al., 2013)
PIG-O
Phosphatidylinositol glycan anchor biosynthesis class O
(Satoh et al., 2013)
PIG-P
Phosphatidylinositol glycan anchor biosynthesis class P
(Satoh et al., 2013)
PIG-Q
Phosphatidylinositol glycan anchor biosynthesis class Q
l(1)i19e, Gpi1, l(1)19-134, l(1)14Cd, i19e
(Satoh et al., 2013)
PIG-S
Phosphatidylinositol glycan anchor biosynthesis class S
(Satoh et al., 2013)
PIG-T
Phosphatidylinositol glycan anchor biosynthesis class T
(Satoh et al., 2013)
PIG-U
Phosphatidylinositol glycan anchor biosynthesis class U
(Satoh et al., 2013)
PIG-V
Phosphatidylinositol glycan anchor biosynthesis class V
(Satoh et al., 2013)
PIG-Wa
Phosphatidylinositol glycan anchor biosynthesis class W a
(Satoh et al., 2013)
PIG-Wb
Phosphatidylinositol glycan anchor biosynthesis class W b
(Satoh et al., 2013)
PIG-X
Phosphatidylinositol glycan anchor biosynthesis class X
(Satoh et al., 2013)
PIG-Z
Phosphatidylinositol glycan anchor biosynthesis class Z
(Satoh et al., 2013)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PIG
PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS GENES
Secondary FlyBase ID(s)
References (2)
FlyBase analysis
FlyBase, 2014-, FlyBase Gene Group information.
FlyBase Gene Group information. [FBrf0225556]
Research paper
Satoh et al., 2013, Development 140(2): 385--394
GPI biosynthesis is essential for rhodopsin sorting at the trans-Golgi network in Drosophila photoreceptors. [FBrf0220328]