Gene Group: NA[+]/K[+] TRANSPORTING P-ATPASE

General Information

Name

NA⁺/K⁺ TRANSPORTING P-ATPASE - ALPHA SUBUNITS

Species

D. melanogaster

Symbol

ATPIIC

FlyBase ID

FBgg0000712

Date last reviewed

2023-03-24

Number of members

Description

The Na⁺/K⁺ transporting P-ATPase α-subunit is the catalytic component of the sodium pump, which catalyzes hydrolysis of ATP coupled with the exchange of Na⁺ and K⁺ ions across the plasma membrane. (Adapted FBrf0155879.)

Notes on Group

In FBrf0220434 and FBrf0155879, 'CG3701' was referred as an α (like) subunit of the Na+/K+ transporting P-ATPase. Subsequently this gene was split into CG45062 and CG45063 (see FBrf0222649). Neither of the resulting gene models contain all the functional domains to be a P-ATPase, and therefore neither are included in this group.

Source Material

The NA⁺/K⁺ TRANSPORTING P-ATPASE - ALPHA SUBUNITS Gene Group has been compiled using the following publication(s): Roy et al., 2013, Baumann et al., 2010, Masly et al., 2006, and Okamura et al., 2003 .

Key Gene Ontology (GO) terms

Molecular Function

P-type sodium:potassium-exchanging transporter activity

Biological Process

establishment or maintenance of transmembrane electrochemical gradient

Cellular Component

membrane

Enzymatic activity

Enzyme name (EC)

Na(+)/K(+)-exchanging ATPase (7.2.2.13)

Related Gene Groups

Parent group(s)