HOX-like (HOXL) homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. They encompass transcription factors encoded by the Hox genes of the Antennapedia and the Bithorax gene complexes and genes closely related in sequence. HOXL transcription factors are major regulators of animal development. (Adapted from FBrf0232555).
The HOX-LIKE TRANSCRIPTION FACTORS exist in two separate gene clusters: the Antennapedia (ANT-C) and Bithorax complexes (BX-C).