FB2020_02, released Apr 14, 2020

Gene Group : HOX-LIKE HOMEOBOX TRANSCRIPTION FACTORS

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General Information
Name
HOX-LIKE HOMEOBOX TRANSCRIPTION FACTORS
Species
D. melanogaster
Symbol
HOXL
FlyBase ID
FBgg0000747
Date last reviewed
2017-07-25
Number of members
17
Description
Description

HOX-like (HOXL) homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. They encompass transcription factors encoded by the Hox genes of the Antennapedia and the Bithorax gene complexes and genes closely related in sequence. HOXL transcription factors are major regulators of animal development. (Adapted from FBrf0232555).

Notes on Group

The HOX-LIKE TRANSCRIPTION FACTORS exist in two separate gene clusters: the Antennapedia (ANT-C) and Bithorax complexes (BX-C).

Source Material
The HOX-LIKE HOMEOBOX TRANSCRIPTION FACTORS Gene Group has been compiled by FlyBase curators using the following publication(s): Bürglin and Affolter, 2016 and Zhong and Holland, 2010 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity
transcription regulatory region sequence-specific DNA binding
Biological Process
regulation of transcription, DNA-templated
Cellular Component
nucleus
Related Gene Groups
Parent group(s)
HOMEOBOX TRANSCRIPTION FACTORS
Other related group(s)
HOX GENE COMPLEX
Members (17)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
abd-A
abdominal A
abdA, iab-2, iab-4, Hab, iab4
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
Abd-B
Abdominal B
AbdB, iab-7, Mcp, Fab-7, iab-6
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
Antp
Antennapedia
ANT-C, Scx, DmAntp, Hu, Humeral
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
bcd
bicoid
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
btn
buttonless
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
cad
caudal
38E.19, cd
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
Dfd
Deformed
DmDfd
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
eve
even skipped
Complementation group F, l(2)46Ce, E(eve)
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
ftz
fushi tarazu
Dm-Ftz
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
ind
intermediate neuroblasts defective
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
lab
labial
F90-2, F24
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
pb
proboscipedia
l(3)04498, proposcipedia
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
ro
rough
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
Scr
Sex combs reduced
Msc, Multiple sex comb
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
Ubx
Ultrabithorax
bx, pbx, Cbx, bithorax, bxd
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
zen
zerknullt
z1, zerknult
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
zen2
zerknullt-related
z2
(Bürglin and Affolter, 2016, Zhong and Holland, 2010)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
HOXL
HOX-LIKE HOMEOBOX TRANSCRIPTION FACTORS
Secondary FlyBase ID(s)
References (3)