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General Information
Name
TORC1 COMPLEX
Species
D. melanogaster
Symbol
TORC1
FlyBase ID
FBgg0000906
Date last reviewed
2018-03-10
Number of members
2
Description
Description

TOR complex 1 (TORC1) is a target of rapamycin (Tor) kinase-containing complex that mediates the response to a variety of stimuli including stress, insulin-like peptides and amino acids. TORC1 regulates processes such as translation, cell growth and autophagy. It can be inhibited by rapamycin. (Adapted from FBrf0238220).

Notes on Group

In yeast and mammalian systems, the ortholog of Lst8 is part of the TORC1 and TORC2 complex. In D.mel, experimental data (FBrf0218417) suggests that Lst8 is not part of the TORC1 complex and has therefore been excluded from this gene group.

Source Material
The TORC1 COMPLEX Gene Group has been compiled by FlyBase curators using the following publication(s): Wang et al., 2012 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
Members (2)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Target of rapamycin
dTOR, mTOR, TORC1, l(2)k17004, FRAP/TOR
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
TORC1
TORC1 COMPLEX
Tor Complex 1
mTORC1
TOR-C1
Secondary FlyBase ID(s)
References (2)