FB2021_02, released April 13, 2021

Gene Group - Pathway: Pvr Signaling Pathway Core Components

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General Information
Name
Pvr Signaling Pathway Core Components
Species
D. melanogaster
Symbol
PVR-C
FlyBase ID
FBgg0000973
Date last reviewed
2020-01-06
Number of members
30
Description
Description

PDGF/VEGF (Platelet-Derived Growth Factor/Vascular Endothelial Growth Factor)-receptor related (Pvr) encodes a receptor tyrosine kinase activated by the binding of PDGF- and VEGF-related factors (Pvf1,Pvf2 or Pvf3). Pvr has been shown to activate the canonical Ras/Raf/MAP kinase (ERK) cascade, the PI3K kinase pathway, TORC1 (FBrf0222697), Rho family small GTPases (FBrf0221764, FBrf0180198) and the JNK cascade (FBrf0180198), in a context-dependent manner. (Adapted from FBrf0222697 and FBrf0221727).

Notes and selected reviews
Biological Process Gene Ontology (GO) term(s)
vascular endothelial growth factor receptor signaling pathway
Related Gene Groups
Parent group(s)
Pvr Signaling Pathway
Physical Interaction Network
Members (30)
For all members:
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PVR-C
Pvr Signaling Pathway Core Components
Platelet-Derived Growth Factor-Vascular Endothelial Growth Factor Receptor-Related Signaling Pathway Core Components
Secondary FlyBase ID(s)
References (16)