Gene Group: 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES

General Information

Name

2-OXOGLUTARATE-DEPENDENT DIOXYGENASES

Species

D. melanogaster

Symbol

OXRPMO2O

FlyBase ID

FBgg0001048

Date last reviewed

2021-03-12

Number of members

Description

Paired donor oxidoreductases, incorporation of molecular oxygen, 2-oxoglutarate as donor, include dehydrogenases that catalyze the reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. 2-oxoglutarate-dependent dioxygenases include dehydrogenases that catalyze the reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.

Notes on Group

Source Material

The 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES Gene Group has been compiled using the following publication(s): Carillo et al., 2020, Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006, and Abrams and Andrew, 2002 .

Key Gene Ontology (GO) terms

Molecular Function

2-oxoglutarate-dependent dioxygenase activity

Biological Process

Cellular Component

Enzymatic activity

Enzyme name (EC)

1.14.11.-

Related Gene Groups

Parent group(s)

DIOXYGENASES

Component group(s)

GAMMA-BUTYROBETAINE HYDROXYLASES

JMJC FAMILY HISTONE DEMETHYLASES

PEPTIDYL-LYSINE 5-DIOXYGENASES

PEPTIDYL-PROLINE DIOXYGENASES

UNCLASSIFIED 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES

Members (54)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

GAMMA-BUTYROBETAINE HYDROXYLASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG5321

(Carillo et al., 2020, FlyBase, 2017-)

CG10814

(Carillo et al., 2020, FlyBase, 2017-)

CG14630

EG:BACR7A4.9, B, anon-1Eb

(Carillo et al., 2020, FlyBase, 2017-)

JMJC FAMILY HISTONE DEMETHYLASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG10600

(FlyBase, 2017-)

JMJD5

Jumonji domain containing 5

(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)

JMJD6

Jumonji domain containing 6

PSR, dPSR, phosphatidylserine receptor

(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)

Kdm2

Lysine demethylase 2

dKDM2, JHDM1, Lysine (K)-specific demethylase 2

(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)

Kdm3

Lysine demethylase 3

JHDM2

(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)

Kdm4A

Lysine demethylase 4A

dKDM4A, Histone demethylase 4A

(Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006)

Kdm4B

Lysine demethylase 4B

Histone demethylase 4B

(Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006)

Kdm5

Lysine demethylase 5

lid, little imaginal discs, l(2)10424, dKDM5/LID

(Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006)

NO66

Nucleolar protein 66

anon-4Bd

(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)

Utx

Utx histone demethylase

dUTX, anon-31BCa

(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)

PEPTIDYL-LYSINE 5-DIOXYGENASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

JMJD6

Jumonji domain containing 6

PSR, dPSR, phosphatidylserine receptor

(FlyBase, 2017-)

Plod

procollagen lysyl hydroxylase

dPlod

(FlyBase, 2017-)

PEPTIDYL-PROLINE DIOXYGENASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG4174

(FlyBase, 2017-)

CG9698

(FlyBase, 2017-, Abrams and Andrew, 2002)

CG11828

(FlyBase, 2017-)

CG15539

(FlyBase, 2017-, Abrams and Andrew, 2002)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

anon-SAGE:Wang-055

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

BP1033

(FlyBase, 2017-)

CG34345

BP1012

(FlyBase, 2017-)

Hph

HIF prolyl hydroxylase

fatiga, fga, l(3)02255, PHD

(FlyBase, 2017-)

PH4αEFB

prolyl-4-hydroxylase-alpha EFB

BcDNA:SD05564

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αMP

prolyl-4-hydroxylase-alpha MP

prolyl-4-hydroxylase-alpha

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αNE1

prolyl-4-hydroxylase-alpha NE1

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αNE2

prolyl-4-hydroxylase-alpha NE2

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αNE3

prolyl-4-hydroxylase-alpha NE3

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αPV

prolyl-4-hydroxylase-alpha PV

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αSG1

prolyl-4-hydroxylase-alpha SG1

SG1, PHαSG1

(FlyBase, 2017-, Abrams and Andrew, 2002)

PH4αSG2

prolyl-4-hydroxylase-alpha SG2

SG2

(FlyBase, 2017-, Abrams and Andrew, 2002)

sud1

sudestada1

(FlyBase, 2017-)

UNCLASSIFIED 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

AlkB

(FlyBase, 2017-)

Asph

Aspartyl β-hydroxylase

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

HSPB1 associated protein 1

(FlyBase, 2017-)

JMJD4

Jumonji domain containing 4

(FlyBase, 2017-)

JMJD7

Jumonji domain containing 7

(FlyBase, 2017-)

Phyhd1

Phytanoyl-CoA dioxygenase domain containing 1

(FlyBase, 2017-)

Tet

Ten-Eleven Translocation (TET) family protein

DMAD, dTet

(FlyBase, 2017-)

Tmlh

Trimethyllysine hydroxylase

(FlyBase, 2017-)

External Data

Equivalent Group(s)

Other resource(s)

Synonyms and Secondary IDs

Synonym(s)

OXRPMO2O

PAIRED DONOR OXIDOREDUCTASES, INCORPORATION OF MOLECULAR OXYGEN, 2-OXOGLUTARATE AS DONOR

2-OXOGLUTARATE-DEPENDENT DIOXYGENASES

Secondary FlyBase ID(s)

References (8)

Report Sections

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