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General Information
Name
BMP Signaling Pathway Core Components
Species
D. melanogaster
Symbol
BMP-C
FlyBase ID
FBgg0001085
Date last reviewed
2019-05-08
Number of members
11
Description
Description
The Bone Morphogenetic Protein (BMP) signaling pathway is one of two branches of Transforming Growth Factor-β family signaling in Drosophila. The binding of a BMP family dimer to a heterodimeric serine/threonine kinase receptor complex results in the phosphorylation of Mad, a member of the Smad family. Mad forms a complex with the co-Smad, Med. This complex translocates into the nucleus and regulates the transcription of target genes in concert with other nuclear cofactors. (Adapted from FBrf0236482.)
Notes and selected reviews
Biological Process Gene Ontology (GO) term(s)
Related Gene Groups
Parent group(s)
Physical Interaction Network
Members (11)
For all members:
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
BMP-C
BMP Signaling Pathway Core Components
Secondary FlyBase ID(s)
References (50)