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General Information
Name
TRANSMEMBRANE RECEPTORS
Species
D. melanogaster
Symbol
TM-R
FlyBase ID
FBgg0001106
Date last reviewed
2021-09-23
Number of members
482
Description
Description
Cell surface transmembrane receptors that bind ligands to elicit cellular responses and mediate cell interactions.
Notes on Group

The TRANSMEMBRANE RECEPTORS gene group is not an fully comprehensive list of receptors, but a collection of receptor families and genes with GO annotations indicating receptor activity.

Source Material
The TRANSMEMBRANE RECEPTORS Gene Group has been compiled by FlyBase curators using the following publication(s): Ni, 2020, Cheng et al., 2019, Mele and Johnson, 2019, Anthoney et al., 2018, Levin and Malik, 2017, Li et al., 2017, Qi et al., 2017, de Mendoza et al., 2016, Feingold et al., 2016, Liu et al., 2016, Okuda et al., 2016, Remnant et al., 2016, Tadros et al., 2016, Xia et al., 2016, Andersen et al., 2015, Han et al., 2015, Hatzihristidis et al., 2015, Hu et al., 2015, Linneweber et al., 2015, Tan et al., 2015, Tomita et al., 2015, Hilbrant et al., 2014, Linnemannstöns et al., 2014, Sopko et al., 2014, Araújo et al., 2013, Bayliss et al., 2013, Chintapalli et al., 2013, Collin et al., 2013, Gasque et al., 2013, Li et al., 2013, Ljaschenko et al., 2013, Ozkan et al., 2013, Vogel et al., 2013, Caers et al., 2012, Chen and Wang, 2012, Chorna and Hasan, 2012, Dupuis et al., 2012, Ohhara et al., 2012, Patel et al., 2012, Posnien et al., 2012, Hansen et al., 2011, Herboso et al., 2011, Ida et al., 2011, Cooper et al., 2010, Croset et al., 2010, Croset et al., 2010, Knipple and Soderlund, 2010, Millard et al., 2010, Somogyi et al., 2010, Aberle, 2009, Anamika et al., 2009, Benton et al., 2009, Biswas et al., 2009, Evans et al., 2009, Lee et al., 2009, Montell, 2009, Robertson, 2009, Veenstra, 2009, Vogt et al., 2009, Zlatic et al., 2009, Andrews et al., 2008, Hattori et al., 2008, Nichols and Vogt, 2008, Pantazis et al., 2008, Yapici et al., 2008, Bates and Whitington, 2007, Dolezelova et al., 2007, Kurucz et al., 2007, Ayoob et al., 2006, Garczynski et al., 2006, Hauser et al., 2006, Hauser et al., 2006, Hummel and Klämbt, 2006, Jorgensen et al., 2006, Cazzamali et al., 2005, Evans and Maqueira, 2005, Gisselmann et al., 2005, Hombria et al., 2005, Lazzaro, 2005, Sattelle et al., 2005, Schnizler et al., 2005, Sudo et al., 2005, Xia et al., 2005, Ahimou et al., 2004, Alvarado et al., 2004, Andersen et al., 2004, Derheimer et al., 2004, Gisselmann et al., 2004, Huang and Klein, 2004, MacLaren et al., 2004, Mitri et al., 2004, Brower, 2003, Park et al., 2003, Robertson et al., 2003, Castellani and Rougon, 2002, Gisselmann et al., 2002, Kanda et al., 2002, Kaupp and Seifert, 2002, Manning et al., 2002, Terman et al., 2002, Brown et al., 2001, Harmar, 2001, Hill et al., 2001, Mezler et al., 2001, Pipes et al., 2001, Brody and Cravchik, 2000, Hynes and Zhao, 2000, Hynes and Zhao, 2000, Littleton and Ganetzky, 2000, Morrison et al., 2000, Tauszig et al., 2000, Walchli et al., 2000, Warr et al., 2000, Josefsson, 1999, Yu and Kolodkin, 1999, Finn et al., 1998, Chen and Struhl, 1996, Cully et al., 1996, and Musacchio and Perrimon, 1996 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Related Gene Groups
Other related group(s)
Members (482)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
5-hydroxytryptamine (serotonin) receptor 1A
5HT1A, 5HT-dro2A, 5-HT1A, 5-HT1ADro, 5-HT
5-hydroxytryptamine (serotonin) receptor 1B
5HT1B, d5-HT1B, 5HT-dro2B, 5-HT1B, 5-HT1BDro
5-hydroxytryptamine (serotonin) receptor 2A
5-HT2, 5-HT2Dro, 5-HT2, 5-HT2Dro, 5-HT2Dro
5-hydroxytryptamine (serotonin) receptor 2B
5-hydroxytryptamine (serotonin) receptor 7
5HT7, 5HT-dro1, 5-HT7, 5-HT7Dro, 5-HT7Dro
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
bride of sevenless
F
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cadherin 96Ca
stit, Stitcher, HD-14, DmHD-14
Cadherin-N
N-cadherin, DN-cadherin, Ncad, N-Cad, DN-Cad
Cadherin-N2
NCad2, CT23007, N-cadherin2
fat
l(2)k07918, l(2)ft, l(2)79/18, CT11259, l(2)fat
kugelei
fat2, fat-like, CT23445, kugel, ftl
Ret oncogene
dRet, DmHD-59
shotgun
DE-cadherin, E-cadherin, E-cad, DE-cad, Ecad
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Adipokinetic hormone receptor
GRHR, AKH receptor, DGRHR, Gonadotropin-releasing hormone receptor
Allatostatin A receptor 1
AlstR, AstAR1, DAR-1, GR, EG:121E7.2
Allatostatin A receptor 2
DAR-2, AR-2, DAR2, ASTR
Crustacean cardioactive peptide receptor
CcapR, CCAP receptor
Cholecystokinin-like receptor at 17D1
CCKLR, CCK-like receptor at 17D1
Cholecystokinin-like receptor at 17D3
DSK-R1, CCK-like receptor at 17D3
Leucine-rich repeat-containing G protein-coupled receptor 1
DLGR1, DLGR-1, Fsh, TSH, FSH, LH/CG receptor
Leucine-rich repeat-containing G protein-coupled receptor 3
DLGR3
Leucine-rich repeat-containing G protein-coupled receptor 4
DLGR4
Myosuppressin receptor 2
DmsR-2, Dromyosuppressin receptor 2
Neuropeptide F receptor
NPFR1, NPF-R, DmNPFR1
RYamide receptor
NepYr, PR4, Neuropeptide Y receptor-like
short neuropeptide F receptor
sNPFR1, sNPFR, NPFR76F, sNPF receptor
Tachykinin-like receptor at 99D
DTKR, Takr99D, l(3)s2222, tachykinin receptor
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Diuretic hormone 31 Receptor
Dh31-R1, Dh31r, Diuretic hormone 31 receptor 1
Pigment-dispersing factor receptor
han, PDF receptor, EG:BACR25B3.3, groom-of-pdf, PDF-receptor
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Calcium-independent receptor for α-latrotoxin
dCirl, latrophilin
starry night
fmi, flamingo, CT20776
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Scavenger receptor class C, type I
dSR-CI, Sr-Cl, dSR-C1, SR-C1
Scavenger receptor class C, type II
Scavenger receptor class C, type III
dSR-CIII
Scavenger receptor class C, type IV
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cyclic nucleotide-gated ion channel subunit A
DmCNGC, Cng, Cyclic-nucleotide-gated ion channel protein
Cyclic nucleotide-gated ion channel subunit B
Cyclic nucleotide-gated ion channel-like
CNG channel-like
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Dopamine 1-like receptor 1
DopR, DopR1, dumb, dDA1, DA1
Dopamine 1-like receptor 2
DopR2, DAMB, DopR99B, dopamine receptor in mushroom bodies, Dopamine receptor 2
Dopamine 2-like receptor
D2R, DD2R
Dopamine/Ecdysteroid receptor
DmDopEcR, dop
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Down syndrome cell adhesion molecule 1
Dscam, Down syndrome cell adhesion molecule, l(2)43Bc, Drosophila Down syndrome cell adhesion molecule, p270
Down syndrome cell adhesion molecule 2
Down syndrome cell adhesion molecule 3
Down syndrome cell adhesion molecule 4
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
frizzled
Fz1, Dfz1, DFz, Frizzled 1, frz
frizzled 2
Dfz2, Dfrz2, fz-2, DFz-2, Dfrizzled2
frizzled 3
Dfz3, Dfrizzled-3, EG:34F3.6
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
metabotropic GABA-B receptor subtype 1
GABABR1, BG:DS00929.6, GABAB-R1, GABAB-R, GABA
metabotropic GABA-B receptor subtype 2
GABABR2, GABAB-R2, GABABR2, GBR
metabotropic GABA-B receptor subtype 3
GABABR3, GABAB-R3
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gustatory receptor 2a
EG:BACN32G11.1, Gr2B1
Gustatory receptor 5a
Tre, trehalose receptor, Gr5A1, han
Gustatory receptor 22b
Gr22bP, Gr2940.4
Gustatory receptor 22d
Gr22dP, Gr2940.2
Gustatory receptor 22f
GR22B.1, Gr22B1
Gustatory receptor 23a
Gr23aB, Gr23aA, GR23A.1, Gr23a.b, Gr23a.a
Gustatory receptor 28b
Gr28b.a, Gr28b.d, Gr28b.e, Gr28be, Gr28bA
Gustatory receptor 39a
Gr39a.a, Gr39a.d, Gr39a.b, Gr39aA, Gr39aD
Gustatory receptor 47a
47A1, Gr47A1
Gustatory receptor 59b
Gr59C1, Gr59D3
Gustatory receptor 64e
Gr64, Gr64A2
Gustatory receptor 64f
Gr64, Gr64A3
Gustatory receptor 98c
Gr98A1, Gr98A2
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
inflated
αPS2, αPS2, PS2, αPS2 integrin, PS2α
Integrin alphaPS4 subunit
αPS4, alphaPS4, ItgαPS4, α-ps4
Integrin alphaPS5 subunit
αPS5, alphaPS5, ItgαPS5, α-PS5
Integrin betanu subunit
βν, betaInt-nu, βInt-ν, βν integrin, βv
multiple edematous wings
αPS1, αPS1, PS1, PS1α, αPS1 integrin
myospheroid
βPS, βPS integrin, β-integrin, βPS-integrin, βPS
scab
αPS3, Volado, Vol, E(Sev-CycE)E93, l(2)51Ea
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
hibris
icon, inappropriate contacts, A69
kin of irre
duf, dumbfounded, Duf/Kirre, Dumbfounded/Kirre
roughest
irreC, irreC-rst, irreC-roughest, rst-irreC, irregular chiasm C-roughest
sticks and stones
43-49
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
klingon
l(3)rN712
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
metabotropic Glutamate Receptor
DmGluRA, mGluRA, Glu-RA, DmGluRA
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
muscarinic Acetylcholine Receptor, A-type
mAChR, mAcR-60C, DM1, A-type mAChR, muscarinic receptor
muscarinic Acetylcholine Receptor, B-type
B-type mAChR
muscarinic Acetylcholine Receptor, C-type
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
nicotinic Acetylcholine Receptor α1
ALS, Dα1, nAcRalpha-96Aa, nAChR, nAcRα-96Aa
nicotinic Acetylcholine Receptor α2
Dα2, SAD, nAcRα-96Ab, nAChR, nAcRalpha-96Ab
nicotinic Acetylcholine Receptor α3
Dα3, nACRalpha-7E, nAChR, nAcRα-7E, nicotinic Acetylcholine Receptor alpha 7E
nicotinic Acetylcholine Receptor α4
Dα4, nAChR, nAcRα-80B, nAcRalpha-80B, redeye
nicotinic Acetylcholine Receptor α5
Dα5, nAChR, BG:DS05899.4, nAcRalpha-34E, nAcRα-34E
nicotinic Acetylcholine Receptor α6
Dα6, nAcRalpha-30D, nAcRα-30D, nAChR, nicotinic Acetylcholine Receptor α 30D
nicotinic Acetylcholine Receptor α7
Dα7, gfA, nAcRα-18C, nAChR, giant fibre A
nicotinic Acetylcholine Receptor β1
ARD, nAcRβ-64B, Dβ1, nAChR, nAcRbeta-64B
nicotinic Acetylcholine Receptor β2
SBD, Dβ2, nAcRbeta-96A, nAChR, second beta-like subunit of Drosophila
nicotinic Acetylcholine Receptor β3
Dβ3, nAcRβ-21C, nAChR, nAcRbeta-21C, nicotinic acetylcholine receptor beta 21C
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Nimrod A
DS00180.5, BG:DS00180.5, j, jaunty
Nimrod C1
BG:DS00180.10, P1, nimrod
Nimrod C3
l(2)br30, l(2)34Fa, l(2)k00811, br30, BG:DS05899.2
Nimrod C4
simu, BG:DS05899.3, six-microns-under, six microns under
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Octopamine receptor in mushroom bodies
GPCR, octopamine receptor
α2-adrenergic-like octopamine receptor
Octopamine β1 receptor
oa2, octopamine receptor 2, DmOctβ1R, OctBeta1
Octopamine β2 receptor
Dm_3R:45121, DmOctβ2R
Octopamine β3 receptor
OctBeta3, DmOctβ3R
Octopamine-Tyramine receptor
TyrR, l(3)neo30, hono, Ocr, honoka
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Odorant receptor 2a
AN4, EG:30B8.7, Olfactory receptor 2F.1
Odorant receptor 19b
Odorant receptor 22a
AN11, DOR22a, Dor53, DmOr22a, 22A.1
Odorant receptor 22b
AN12, Dor67, 22A.2, DOR22A.2
Odorant receptor 35a
BG:BACR44L22.5, 35a
Odorant receptor 46a
Or46aA, Or46b, Or46aB, AN9, AN8
Odorant receptor 47a
AN10, DOR24, 47a
Odorant receptor 67d
DmOr67d
Odorant receptor 69a
Or69b, Or69aA, Or69aB
Odorant receptor 85e
Odorant receptor 104, Dor104
Odorant receptor co-receptor
Or83b
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Adenosine receptor
DmAdoR
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Anaplastic lymphoma kinase
DAlk
breathless
dev, FGFR, DFR2, DFGF-R1, FGF receptor
Cadherin 96Ca
stit, Stitcher, HD-14, DmHD-14
Discoidin domain receptor
doughnut on 2
doughnut
derailed
lio, linotte
Derailed 2
doughnut-like, dnl
Epidermal growth factor receptor
DER, top, flb, Elp, torpedo
Eph receptor tyrosine kinase
dek, lincRNA.923, Deph, CT3831, Eph receptor
heartless
DFR1, FGFR, FGF receptor, fibroblast growth factor receptor, DmHD-38
Insulin-like receptor
dInR, insulin receptor, DIR, sprout, IR
Neurospecific receptor kinase
Dnrk, DmHD-434, nrtk_dros
off-track
Dtrk, Dtkr
PDGF- and VEGF-receptor related
PDGF/VEGF receptor, VEGFR, VEGF receptor, stai
Ret oncogene
dRet, DmHD-59
Ror
Dror, DmHD-2
sevenless
DmHD-265, DROSEV1
Tie-like receptor tyrosine kinase
RTK, DPR1
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
neither inactivation nor afterpotential E
Rh1, rhodopsin, Rhodopsin 1, Rh-1, Rhodopsin-1
Rhodopsin 7
rhodopsin
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
smoothened
dSmo, smooth
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
thickveins
str, Thickvein, Brk25D, l(2)04415, slater
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Octopamine-Tyramine receptor
TyrR, l(3)neo30, hono, Ocr, honoka
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
domeless
vsp, mom, l(1)G0282, l(1)G0264, l(1)G0367
Notch
Ax, spl, fa, NICD, Abruptex
patched
tuf, rubr, Ptch
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
TM-R
TRANSMEMBRANE RECEPTORS
Signaling Receptor
Secondary FlyBase ID(s)
References (120)