FB2025_05 , released December 11, 2025
Complex: DNA POLYMERASE ZETA
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General Information
Name
DNA POLYMERASE ZETA
Species
D. melanogaster
Symbol
DNAPOLZ
FlyBase ID
FBgg0001212
Date last reviewed
Number of members
4
Description
Description
DNA polymerase zeta is one of several translesion synthesis polymerases that act to promote replication through DNA lesions that would otherwise stall the replicative polymerases. It is a heterotetramer, in which the catalytic subunit is encoded by DNApol-ζ, and is specialized for the extension step of lesion bypass. (Adapted from PMID:30005324.)
Notes on Group

The products Pol31 and Pol32 are accessory subunits of both DNA POLYMERASE DELTA and DNA POLYMERASE ZETA.

Source Material
The DNA POLYMERASE ZETA Gene Group has been compiled using the following publication(s): Marygold et al., 2020 .
Key Gene Ontology (GO) terms
Biological Process
Enzymatic activity
Enzyme name (EC)
DNA-directed DNA polymerase (2.7.7.7)
Related Gene Groups
Parent group(s)
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
DNAPOLZ
DNA POLYMERASE ZETA
Secondary FlyBase ID(s)
References (3)