FB2025_05 , released December 11, 2025
Gene Group: M1 METALLOPEPTIDASES
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General Information
Name
M1 METALLOPEPTIDASES
Species
D. melanogaster
Symbol
M1P
FlyBase ID
FBgg0001422
Date last reviewed
2020-06-08
Number of members
17
Description
Description
M1 metallopeptidases belong to MEROPS family M1. All members of the family act on the N-terminus of polypeptides, many of them being aminopeptidases. The family also contains pyroglutamyl-peptidase II, an omega peptidase that releases pyroglutamate from thyrotropin-releasing hormone, and some dipeptidases. (Adapted from FBrf0239469.)
Notes on Group
Source Material
The M1 METALLOPEPTIDASES Gene Group has been compiled using the following publication(s): Li et al., 2022, Schulz et al., 2001, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
metallopeptidase activity
Biological Process
proteolysis
Cellular Component
Related Gene Groups
Parent group(s)
METALLOPEPTIDASES
PEPTIDASE FAMILY M1
Members (17)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)

[MEROPS Family M1](https://www.ebi.ac.uk/merops/cgi-bin/famsum?family=m1)

Synonyms and Secondary IDs
Synonym(s)
M1 METALLOPEPTIDASES
M1P
M1
Secondary FlyBase ID(s)
References (5)