FB2025_01 , released February 20, 2025
Gene Group: TASPASES
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General Information
Name
TASPASES
Species
D. melanogaster
Symbol
TASP
FlyBase ID
FBgg0001440
Date last reviewed
2020-06-08
Number of members
1
Description
Description
Taspases belong to MEROPS family T2. They are threonine endopeptidases that catalyse cis-cleavage to generate an active heterodimer of alpha and beta subunits, as well as cleavage of aspartyl bonds in other substrates, notably the trx protein in Drosophila and the Mixed-Lineage Leukemia (MLL) protein in humans. (Adapted from FBrf0212858.)
Notes on Group

The TASPASES gene group contains only one member.

Source Material
The TASPASES Gene Group has been compiled using the following publication(s): Wünsch et al., 2015, Hsieh et al., 2003, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
threonine-type endopeptidase activity
Biological Process
proteolysis
Cellular Component
cytoplasm
Enzymatic activity
Enzyme name (EC)
3.4.25.-
Related Gene Groups
Parent group(s)
THREONINE PEPTIDASES
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Tasp1
Taspase 1
l(3)72Dl
(FlyBase, 2017-, Wünsch et al., 2015, Hsieh et al., 2003, Rawlings and Barrett, 1996-)
External Data
Equivalent Group(s)
Other resource(s)

[MEROPS Family T2](https://www.ebi.ac.uk/merops/cgi-bin/famsum?family=t2)

Synonyms and Secondary IDs
Synonym(s)
TASPASES
TASP
T2
Secondary FlyBase ID(s)
References (5)