FB2025_01 , released February 20, 2025
Gene Group: PROTEASOME NON-CATALYTIC BETA SUBUNITS
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General Information
Name
PROTEASOME NON-CATALYTIC BETA SUBUNITS
Species
D. melanogaster
Symbol
PSM20SB-NC
FlyBase ID
FBgg0001457
Date last reviewed
2020-06-11
Number of members
6
Description
Description
The catalytic core 20S proteasome is a threonine protease comprising alpha and beta subunits. The active-site threonine residue is at the N-terminus of the beta subunits, though only three of the seven eukaryotic beta subunits (beta1, beta2 and beta5) retain an intact active site. The other beta subunits have non-catalytic roles. (Adapted from FBrf0215459 and PMID:28583440).
Notes on Group
Source Material
The PROTEASOME NON-CATALYTIC BETA SUBUNITS Gene Group has been compiled using the following publication(s): Belote and Zhong, 2009, Ma et al., 2002, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
proteasome core complex, beta-subunit complex
Related Gene Groups
Parent group(s)
PROTEASOME BETA SUBUNITS
THREONINE-TYPE NON-PEPTIDASE HOMOLOGS
Members (6)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Prosβ3
Proteasome β3 subunit
β3
(Belote and Zhong, 2009, Ma et al., 2002, Rawlings and Barrett, 1996-)
Prosβ4
Proteasome β4 subunit
β4
(Belote and Zhong, 2009, Ma et al., 2002, Rawlings and Barrett, 1996-)
Prosβ4R1
Proteasome β4 subunit-related 1
(Belote and Zhong, 2009, Ma et al., 2002)
Prosβ4R2
Proteasome β4 subunit-related 2
(Belote and Zhong, 2009, Ma et al., 2002)
Prosβ6
Proteasome β6 subunit
Pros26, DTS5, l(3)73Ai, β6, DTS-5
(Belote and Zhong, 2009, Ma et al., 2002, Rawlings and Barrett, 1996-)
Prosβ7
Proteasome β7 subunit
Prosβ4, β7
(Belote and Zhong, 2009, Ma et al., 2002)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PSM20SB-NC
PROTEASOME NON-CATALYTIC BETA SUBUNITS
Secondary FlyBase ID(s)
References (4)